Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 clinical trials

Explore recruiting aclf is a syndrome that occurs in patients with chronic liver disease with or without previously diagnosed cirrhosis which is characterized by acute hepatic decompensation resulting in liver failure jaundice and prolongation of inr one or more extrahepatic organ failures renal brain coagulation respiratory cardiovascular and is associated with increased mortality within 28 days and up to 3 months from onset grade 1 aclf has a 15 risk of mortality at 28 days the study population will consist of up to 78 subjects with grade 1 3 aclf limited to 3 organ failures and a baseline clif c aclf crp score of 35 and 60 clinical trials.

Also recruiting in Europe

Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 trials registered in the EU Clinical Trials Information System (CTIS). These are outside the "near me" matcher above - open a study for full details.

Phase2, double-blind, randomized, placebo-controlled, multicentre study to evaluation the safety, efficacy, and pharmacokinetics of TAK-242 and Granulocyte Colony-Stimulating Factor (G-CSF) (G-TAK) in subjects with severe alcoholic hepatitis (sAH) and acute-on-chronic liver failure (ACLF).

Germany, Spain, Portugal

Therapeutic exploratory (Phase II) EU CTIS Study details

Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 trials by city

Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Toronto Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Vancouver Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Montreal Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Calgary Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Edmonton Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Ottawa Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Winnipeg Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Quebec City Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Hamilton Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Kitchener Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in London Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Halifax Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in New York Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Los Angeles Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Chicago Aclf Is A Syndrome That Occurs In Patients With Chronic Liver Disease With Or Without Previously Diagnosed Cirrhosis Which Is Characterized By Acute Hepatic Decompensation Resulting In Liver Failure Jaundice And Prolongation Of Inr One Or More Extrahepatic Organ Failures Renal Brain Coagulation Respiratory Cardiovascular And Is Associated With Increased Mortality Within 28 Days And Up To 3 Months From Onset Grade 1 Aclf Has A 15 Risk Of Mortality At 28 Days The Study Population Will Consist Of Up To 78 Subjects With Grade 1 3 Aclf Limited To 3 Organ Failures And A Baseline Clif C Aclf Crp Score Of 35 And 60 in Houston

Other conditions

Obesity Type 2 diabetes Type 1 diabetes Prediabetes Weight loss Metabolic syndrome High cholesterol High triglycerides High blood pressure PCOS Hypothyroidism Thyroid disease Gout Fatty liver disease (NAFLD/NASH) Heart failure Coronary artery disease Atrial fibrillation Stroke Stroke recovery Peripheral artery disease Pulmonary hypertension Deep vein thrombosis Chronic kidney disease Diabetic kidney disease