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New treatment option for Familial Adenomatous Polyposis (FAP)
Official title Evaluation of the Ileo-anal Pouch in FAP (ENDOPOL)
ClinicalTrials.gov ID: NCT07726771
What this study is testing
- What it's testing
- This international, multi-centre randomised controlled trial will compare dye-based chromoendoscopy with virtual chromoendoscopy, using NBI/BLI, for adenoma detection during routine surveillance pouchoscopy in adults with familial adenomatous polyposis (FAP) and an ileal pouch-anal anastomosis (IPAA). The estimated study duration is 2 years.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- ALL of the following:
- Diagnosis of FAP i.e., at least one of following:
- Genetic diagnosis: proven APC germline mutation OR
- Clinical diagnosis: \>100 colorectal adenomas in combination with a positive family history of FAP
- Have an ileal-pouch anal anastomosis (IPAA), either after primary proctocolectomy or secondary proctectomy after initial colectomy and ileorectal or...
You likely can't join if
- ANY of the following
- Diagnosis of FAP i.e., at least one of following:
- Genetic diagnosis: proven APC germline mutation OR
- Clinical diagnosis: \>100 colorectal adenomas in combination with a positive family history of FAP
- Have an ileal-pouch anal anastomosis (IPAA), either after primary proctocolectomy or secondary proctectomy after initial colectomy and ileorectal or...
- Age ≥ 18 years
See the full eligibility criteria
- ALL of the following:
- Diagnosis of FAP i.e., at least one of following:
- Genetic diagnosis: proven APC germline mutation OR
- Clinical diagnosis: \>100 colorectal adenomas in combination with a positive family history of FAP
- Have an ileal-pouch anal anastomosis (IPAA), either after primary proctocolectomy or secondary proctectomy after initial colectomy and ileorectal or ileosigmoidal anastomosis (IRA/ISA)
- Age ≥ 18 years
- ANY of the following
- Diagnosis of FAP i.e., at least one of following:
- Genetic diagnosis: proven APC germline mutation OR
- Clinical diagnosis: \>100 colorectal adenomas in combination with a positive family history of FAP
- Have an ileal-pouch anal anastomosis (IPAA), either after primary proctocolectomy or secondary proctectomy after initial colectomy and ileorectal or ileosigmoidal anastomosis (IRA/ISA)
- Age ≥ 18 years
The study team makes the final eligibility decision.
Where it's taking place
- London, London, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include London, London, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.