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Official title Effects of Hard Gum Chewing on Facial Soft Tissue Morphology
ClinicalTrials.gov ID: NCT07726511
What this study is testing
- What it's testing
- This pilot clinical trial will evaluate whether intentional chewing of a standardized hard chewing gum for 4 weeks produces measurable changes in facial morphology in healthy adults. Twenty participants aged 20-40 years will undergo three-dimensional facial imaging (3dMD) at baseline (T0), after the 4-week chewing intervention (T1), and following a 4-5-week washout period (T2).
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 40
You may be able to join if
- Healthy, non-smoking adults.
- Age 20 to 40 years.
- Presence of a full dentition from central incisor to first molar in all four quadrants, excluding second molars.
- Stable occlusion with no ongoing orthodontic treatment or myofunctional therapy.
- Ability and willingness to comply with the prescribed hard-gum chewing regimen for 4 weeks and attend all study visits.
You likely can't join if
- Age younger than 20 years or older than 40 years.
- Evident facial asymmetry from a frontal view.
- Signs or symptoms of temporomandibular disorders (TMD) according to the Diagnostic Criteria for TMD (DC/TMD).
- Less than the normal range of condylar motion during maximum opening and closing.
- Parafunctional habits such as bruxism with pain, clenching, or habitual gum chewing for more than 1 hour per day.
- History of major craniofacial trauma, orthognathic surgery, or congenital craniofacial anomalies.
See the full eligibility criteria
- Healthy, non-smoking adults.
- Age 20 to 40 years.
- Presence of a full dentition from central incisor to first molar in all four quadrants, excluding second molars.
- Stable occlusion with no ongoing orthodontic treatment or myofunctional therapy.
- Ability and willingness to comply with the prescribed hard-gum chewing regimen for 4 weeks and attend all study visits.
- Ability to provide written informed consent.
- Age younger than 20 years or older than 40 years.
- Evident facial asymmetry from a frontal view.
- Signs or symptoms of temporomandibular disorders (TMD) according to the Diagnostic Criteria for TMD (DC/TMD).
- Less than the normal range of condylar motion during maximum opening and closing.
- Parafunctional habits such as bruxism with pain, clenching, or habitual gum chewing for more than 1 hour per day.
- History of major craniofacial trauma, orthognathic surgery, or congenital craniofacial anomalies.
- Ongoing orthodontic treatment or recent removal of fixed appliances (\<6 months).
- Significant malocclusion or missing teeth in the anterior or premolar-first molar region that may affect mastication.
- Systemic diseases or medications affecting muscle or bone metabolism.
- Previous use of botulinum toxin (Botox) within the last 6 months or anticipated use during the study period.
- Pregnancy or lactation.
- Allergy or intolerance to the chewing gum ingredients.
The study team makes the final eligibility decision.
Where it's taking place
- Farmington, Connecticut, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 40 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Farmington, Connecticut, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.