BridgeMD
New treatment option for Type 2 Diabetes
Official title Legume Flour Particle Size and Metabolic Responses to Bread
ClinicalTrials.gov ID: NCT07716059
What this study is testing
- What it's testing
- The aim of the study is to investigate the effect of partial replacement of wheat flour by legume flour of different particle sizes on postprandial glucose responses and appetite sensations in healthy subjects and patients with type 2 diabetes. Subjects will consume a portion of bread enriched with legume flours yielding 50 g of available carbohydrates as breakfast meal.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75
You may be able to join if
- Cohort Healthy Participants
- Age: Adults aged 18-35 years.
- Health Status: Healthy individuals with no diagnosed chronic diseases, including diabetes, cardiovascular disease, or gastrointestinal disorders.
- Body Mass Index (BMI): 18.5-27 kg/m² (normal to overweight range).
- Fasting Glucose: Normal fasting plasma glucose (\<100 mg/dL or \<5.6 mmol/L).
You likely can't join if
- Diagnosed chronic diseases: Diabetes (type 1 or type 2), cardiovascular disease, kidney or liver disease, gastrointestinal disorders (e.g., celiac...
- Abnormal glucose metabolism: Fasting plasma glucose ≥100 mg/dL (≥5.6 mmol/L) or HbA1c ≥5.7%.
- Medication use: Regular use of medications that affect glucose metabolism, insulin sensitivity, or digestion (e.g., metformin, corticosteroids, GLP-1...
- Allergies or intolerances: Allergy or intolerance to wheat, chickpeas, gluten, or other ingredients used in the study foods.
- Pregnancy or lactation: Women who are pregnant, breastfeeding, or planning pregnancy during the study period.
- Recent major weight change: Significant weight loss or gain (\>5% body weight) in the past 3 months.
See the full eligibility criteria
- Cohort Healthy Participants
- Age: Adults aged 18-35 years.
- Health Status: Healthy individuals with no diagnosed chronic diseases, including diabetes, cardiovascular disease, or gastrointestinal disorders.
- Body Mass Index (BMI): 18.5-27 kg/m² (normal to overweight range).
- Fasting Glucose: Normal fasting plasma glucose (\<100 mg/dL or \<5.6 mmol/L).
- No regular use of medications known to affect glucose metabolism (e.g., insulin, metformin, corticosteroids).
- Ability and willingness to comply with study procedures, including continuous glucose monitoring and standardized test meals.
- Informed Consent: Ability to understand and provide written informed consent.
- Diagnosed chronic diseases: Diabetes (type 1 or type 2), cardiovascular disease, kidney or liver disease, gastrointestinal disorders (e.g., celiac disease, inflammatory bowel disease).
- Abnormal glucose metabolism: Fasting plasma glucose ≥100 mg/dL (≥5.6 mmol/L) or HbA1c ≥5.7%.
- Medication use: Regular use of medications that affect glucose metabolism, insulin sensitivity, or digestion (e.g., metformin, corticosteroids, GLP-1 analogs).
- Allergies or intolerances: Allergy or intolerance to wheat, chickpeas, gluten, or other ingredients used in the study foods.
- Pregnancy or lactation: Women who are pregnant, breastfeeding, or planning pregnancy during the study period.
- Recent major weight change: Significant weight loss or gain (\>5% body weight) in the past 3 months.
- Extreme physical activity: Competitive athletes or individuals engaging in extreme exercise regimens that could influence glucose metabolism.
- Inability to comply: Individuals unable or unwilling to follow study procedures, including continuous glucose monitoring and standardized test meals. Cohort 2: Participants with Type 2 Diabetes Mellitus Men and women...
The study team makes the final eligibility decision.
Where it's taking place
- Athens, Attica, Greece
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Athens, Attica, Greece. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.