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New treatment option for Muscle Strength
Official title A Pilot Study of HME Amino Acid Supplementation on Strength, Performance, and Recovery in Trained Adult Males
ClinicalTrials.gov ID: NCT07715201
What this study is testing
- What it's testing
- This pilot randomized controlled trial evaluates HME (Human Muscle Equivalent), a free-form amino acid supplement formulated to match the amino acid composition of human skeletal muscle, taken at its Health Canada licensed dose (3 g powder plus one 50 mg slow-release beta-alanine capsule daily). Trained adult males (competitive athletes or certified fitness professionals) are randomized to HME or an identical-appearing placebo for 10 weeks: a 2-week supplement-only lead-in followed by 8 weeks of supplement plus supervised resistance training.
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45, men only. Healthy volunteers may be eligible.
You may be able to join if
- Age 18 to 45 years inclusive
- Biological male
- Active competitive athlete in a recognized sport OR certified fitness professional (personal trainer, strength and conditioning coach, or equivalent)
- Minimum 3 structured resistance-training sessions per week for at least 1 year continuously
- Habitual protein intake 1.2 to 2.0 g/kg/day confirmed by 7-day food diary at screening
You likely can't join if
- Use of anabolic steroids, SARMs, prohormones, or beta-alanine supplements (other than the study product) within 8 weeks of screening
- Current use of any amino acid supplement or weight-gainer product not cleared by the research coordinator
- Currently in an active competitive season with non-negotiable training demands the investigator determines are incompatible with the supervised...
- Musculoskeletal injury in the preceding 3 months affecting ability to perform study assessments or training
- Any medical condition, medication, or dietary restriction that in the Medical Officer's opinion would affect the safety or validity of participation
- Participation in another intervention study within 4 weeks of screening
See the full eligibility criteria
- Age 18 to 45 years inclusive
- Biological male
- Active competitive athlete in a recognized sport OR certified fitness professional (personal trainer, strength and conditioning coach, or equivalent)
- Minimum 3 structured resistance-training sessions per week for at least 1 year continuously
- Habitual protein intake 1.2 to 2.0 g/kg/day confirmed by 7-day food diary at screening
- Current creatine users willing to use study-provided creatine monohydrate 5 g/day; non-users willing not to initiate creatine during the trial
- Able to provide written informed consent in English
- Willing and able to attend all supervised training sessions and assessment visits for 10 weeks
- Access to a digital kitchen scale or willing to obtain one for food-record completion
- Use of anabolic steroids, SARMs, prohormones, or beta-alanine supplements (other than the study product) within 8 weeks of screening
- Current use of any amino acid supplement or weight-gainer product not cleared by the research coordinator
- Currently in an active competitive season with non-negotiable training demands the investigator determines are incompatible with the supervised programme
- Musculoskeletal injury in the preceding 3 months affecting ability to perform study assessments or training
- Any medical condition, medication, or dietary restriction that in the Medical Officer's opinion would affect the safety or validity of participation
- Participation in another intervention study within 4 weeks of screening
- Unwillingness to standardize creatine intake per protocol (current users) or to abstain from initiating creatine (non-users)
The study team makes the final eligibility decision.
Where it's taking place
- Toronto, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Toronto, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.