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New treatment option for Not Applicable - Healthy Adult Participants
Official title Study of XmAb412 in Healthy Participants
ClinicalTrials.gov ID: NCT07713485
What this study is testing
What is XmAb412 Monoclonal Bispecific Antibody?
XmAb412 Monoclonal Bispecific Antibody is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for not applicable - healthy adult participants.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This Phase 1 Study will evaluate the safety, tolerability, pharmacokinectics and pharmacodynamics of XmAb412 in healthy adult participants
- Phase 1: an early, usually small safety study
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 55. Healthy volunteers may be eligible.
You may be able to join if
- Age 18-55 years old
- Must be in good health with no significant medical history
- BMI 18-35 kg/m2
- Contraceptive use consistent with local regulations
- Able and willing to provide written informed consent
You likely can't join if
- Any physical condition that prohibits study completion
- Known hypersensitivity to the trial intervention or any of its components
- HIV, hepatitis B and hepatitis C positive
- Clinically significant abnormal ECG
- Use of other investigational products within 5 half lives from Screening
- Blood or plasma donation within 60 days from Screening
See the full eligibility criteria
- Age 18-55 years old
- Must be in good health with no significant medical history
- BMI 18-35 kg/m2
- Contraceptive use consistent with local regulations
- Able and willing to provide written informed consent
- Any physical condition that prohibits study completion
- Known hypersensitivity to the trial intervention or any of its components
- HIV, hepatitis B and hepatitis C positive
- Clinically significant abnormal ECG
- Use of other investigational products within 5 half lives from Screening
- Blood or plasma donation within 60 days from Screening
- Pregnant or breastfeeding Other protocol defined inclusion/exclusion criteria apply
The study team makes the final eligibility decision.
Where it's taking place
- Joondalup, Western Australia, Australia
- Nedlands, Western Australia, Australia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Joondalup, Western Australia, Australia; Nedlands, Western Australia, Australia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.