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New treatment option for Healthy Volunteers
Official title A Study to Evaluate the Absorption, Distribution, Metabolism, and Excretion of [14C]-MRM-3379
ClinicalTrials.gov ID: NCT07712718
What this study is testing
What is [14C]-MRM-3379?
[14C]-MRM-3379 is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for healthy volunteers.
Also referred to as MRM-3379.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This is a Phase 1, open label study in healthy male participants to study the Absorption, Distribution, Metabolism, and Excretion of [14C]-MRM-3379 drug following a single oral dose.
- Phase 1: an early, usually small safety study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 55, men only. Healthy volunteers may be eligible.
You may be able to join if
- Male of any race, between 18 and 55 years of age, inclusive.
- Body mass index between 18.0 and 32.0 kg/m2, inclusive, and a body weight between 50 and 110 kg, inclusive.
- In good health, as determined by medical history, and as assessed by the investigator (or designee).
- Able to comprehend and are willing to sign the ICF and abide by the trial restrictions.
You likely can't join if
- History of or current medical condition that would place the participant at risk from study participation.
- Administration of any vaccine within 30 days prior to dosing.
- Use or intend to use any medications/products known to alter drug absorption, metabolism, or elimination processes, including St. John's wort, within...
- Participation in a clinical trial involving administration of an IMP (new chemical entity) in the past 30 days or 5 half-lives of that drug (if...
- Have previously completed or withdrawn from this trial or any other trial investigating MRM-3379 or have previously received MRM-3379.
- Participants who have previously been dosed in \>2 radiolabeled drug studies in the last 12 months. For participants who have previously been dosed...
See the full eligibility criteria
- Male of any race, between 18 and 55 years of age, inclusive.
- Body mass index between 18.0 and 32.0 kg/m2, inclusive, and a body weight between 50 and 110 kg, inclusive.
- In good health, as determined by medical history, and as assessed by the investigator (or designee).
- Able to comprehend and are willing to sign the ICF and abide by the trial restrictions.
- History of or current medical condition that would place the participant at risk from study participation.
- Administration of any vaccine within 30 days prior to dosing.
- Use or intend to use any medications/products known to alter drug absorption, metabolism, or elimination processes, including St. John's wort, within 30 days prior to dosing, considered to potentially impact participant...
- Participation in a clinical trial involving administration of an IMP (new chemical entity) in the past 30 days or 5 half-lives of that drug (if known) prior to dosing, whichever is longer.
- Have previously completed or withdrawn from this trial or any other trial investigating MRM-3379 or have previously received MRM-3379.
- Participants who have previously been dosed in \>2 radiolabeled drug studies in the last 12 months. For participants who have previously been dosed in ≤2 radiolabeled drug studies within the last 12 months, the previous...
- Participants with exposure to significant diagnostic or therapeutic radiation or current employment in a job requiring radiation exposure monitoring within 12 months prior to check-in.
- Participants who, in the opinion of the investigator (or designee), should not participate in this trial.
The study team makes the final eligibility decision.
Where it's taking place
- Madison, Wisconsin, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 55 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Madison, Wisconsin, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.