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Compares treatment options for Airway Occlusion Pressure
Official title Airway Occlusion Pressure (P0.1) Guided Pressure Support Ventilation Versus Conventional Management in Weaning Window Patients
ClinicalTrials.gov ID: NCT07709182
What this study is testing
- What it's testing
- This study aims to determine whether Airway Occlusion Pressure (P0.1) Guided Pressure Support Ventilation is superior to conventional management for patients in weaning windows.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 and older
You may be able to join if
- Mechanically ventilated adult patients ≥ 21 years.
- Patients on pressure support ventilation for at least 24 hours and clinically determined to be in the weaning window (transition between assisted...
- Hemodynamically stable [mean arterial pressure (MAP) ≥60 mmHg].
- All patients will be required to have light sedation with a Richmond Agitation-Sedation Scale (RASS) score between -1 and 0 to allow reliable...
You likely can't join if
- Patients with neuromuscular disorders affecting respiratory drive
- Glasgow Coma Scale (GCS) score below 8
- Cervical spinal cord injury
- Receipt of neuromuscular blockers within the previous 24 hours
- Morbid obesity resulting in unreliable respiratory mechanics
- Pregnancy
See the full eligibility criteria
- Mechanically ventilated adult patients ≥ 21 years.
- Patients on pressure support ventilation for at least 24 hours and clinically determined to be in the weaning window (transition between assisted ventilation and spontaneous ventilation) with improving respiratory...
- Hemodynamically stable [mean arterial pressure (MAP) ≥60 mmHg].
- All patients will be required to have light sedation with a Richmond Agitation-Sedation Scale (RASS) score between -1 and 0 to allow reliable assessment of respiratory drive.
- Patients with neuromuscular disorders affecting respiratory drive
- Glasgow Coma Scale (GCS) score below 8
- Cervical spinal cord injury
- Receipt of neuromuscular blockers within the previous 24 hours
- Morbid obesity resulting in unreliable respiratory mechanics
- Pregnancy
- Deep sedation defined as RASS ≤ -2
- Hemodynamic instability requiring escalating vasopressor support.
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, Al Gharbia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, Al Gharbia, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.