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New treatment option for Onchocerciasis (River Blindness)
Official title Expanding Access to Preventive Chemotherapy Among Mobile and Migrant Populations
ClinicalTrials.gov ID: NCT07707817
What this study is testing
What is Albendazole 400 mg?
Albendazole 400 mg is an investigational medicine, given as a treatment applied to the skin, being studied as a potential treatment for onchocerciasis (river blindness).
Also referred to as Mebendazole.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Neglected Tropical Diseases (NTDs) are among the most common groups of diseases affecting over one billion people globally and are disproportionately concentrated in remote, underserved, and marginalized communities. Efforts toward NTD elimination have largely relied on preventive chemotherapy (PC), large-scale distribution of free, safe, and effective medicines to at-risk populations.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 5 and older. Healthy volunteers may be eligible.
You may be able to join if
- Participants will be eligible for inclusion if they:
- Are children aged 5-14 years or adult heads of households residing in households identified as belonging to mobile or migrant populations.
- Reside permanently or semi-permanently within the study communities
- Have missed one or more previous rounds of onchocerciasis and/or lymphatic filariasis MDA.
- Are willing to provide the required biological specimens and participate in interviews, surveys, and participatory workshops or discussions as...
You likely can't join if
- Participants will be excluded if they:
- Are temporary visitors without meaningful residence in the study communities.
- Do not belong to the identified mobile or migrant populations targeted by the study.
- Are unable or unwilling to provide the required biological specimens or participate in study procedures.
- Decline informed consent or assent, or whose parent or guardian declines consent for participation.
- Are severely ill or have medical conditions that, in the opinion of study personnel, would make participation unsafe or inappropriate.
See the full eligibility criteria
- Participants will be eligible for inclusion if they:
- Are children aged 5-14 years or adult heads of households residing in households identified as belonging to mobile or migrant populations.
- Reside permanently or semi-permanently within the study communities
- Have missed one or more previous rounds of onchocerciasis and/or lymphatic filariasis MDA.
- Are willing to provide the required biological specimens and participate in interviews, surveys, and participatory workshops or discussions as required by the study protocol.
- Provide informed consent or assent with parental/guardian consent where applicable for minors.
- Participants will be excluded if they:
- Are temporary visitors without meaningful residence in the study communities.
- Do not belong to the identified mobile or migrant populations targeted by the study.
- Are unable or unwilling to provide the required biological specimens or participate in study procedures.
- Decline informed consent or assent, or whose parent or guardian declines consent for participation.
- Are severely ill or have medical conditions that, in the opinion of study personnel, would make participation unsafe or inappropriate.
The study team makes the final eligibility decision.
Where it's taking place
- Ondo, Ondo, Taraba and Akwa Ibom, Nigeria
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 5 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ondo, Ondo, Taraba and Akwa Ibom, Nigeria. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.