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Compares treatment options for COPD
Official title Continuous Versus High Intensity Interval Exercise in Chronic Obstructive Pulmonary Disease
ClinicalTrials.gov ID: NCT07707271
What this study is testing
- What it's testing
- Chronic Obstructive Pulmonary Disease (COPD) is characterized by exercise intolerance, which is a prognostic factor of disease severity and mortality and is usually attributed to ventilatory limitations. Emerging evidence indicates that cerebral oxygenation may also be an important contributor, being impaired both at rest and during exercise in COPD patients.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Adults
You may be able to join if
- Clinical diagnosis of COPD based on smoking history (pack/years) or exposure to other risk factors and post bronchodilation forced expiratory volume...
- Resting arterial oxygen partial pressure at room air \>60 mmHg, according to recent (within a week) arterial blood gases assessment
- Disease being stable and treated optimal, based on current GOLD guidelines.
- Provision of informed written signed consent prior to study entry
You likely can't join if
- Recent respiratory infection or exacerbation (as indicated by deterioration of respiratory symptoms, hospital admission and/or change in medication...
- Changes in COPD medication with the past month
- History of asthma and/or reversible airway obstruction (post bronchodilation FEV1/ FVC \>0.7)
- Pulmonary hypertension
- Congestive heart failure (Left Ventricle Ejection Fraction \<50% in recent echocardiography)
- Severe peripheral artery disease
See the full eligibility criteria
- Clinical diagnosis of COPD based on smoking history (pack/years) or exposure to other risk factors and post bronchodilation forced expiratory volume (FEV1) to forced vital capacity (FVC) ratio \<0.7
- Resting arterial oxygen partial pressure at room air \>60 mmHg, according to recent (within a week) arterial blood gases assessment
- Disease being stable and treated optimal, based on current GOLD guidelines.
- Provision of informed written signed consent prior to study entry
- Recent respiratory infection or exacerbation (as indicated by deterioration of respiratory symptoms, hospital admission and/or change in medication within the previous month), within the past 3 months
- Changes in COPD medication with the past month
- History of asthma and/or reversible airway obstruction (post bronchodilation FEV1/ FVC \>0.7)
- Pulmonary hypertension
- Congestive heart failure (Left Ventricle Ejection Fraction \<50% in recent echocardiography)
- Severe peripheral artery disease
- Chronic Kidney disease with eGFR \< 30 ml/min (KDIGO stages 3b, 4 ,5)
- Active acute or chronic infectious diseases
- Active malignant disease or hematologic disorder under treatment
- History of neuromuscular disorder
- History of severe intellectual disability or mental disorder
- Any contradiction to moderate-high intensity exercise or cardiopulmonary exercise testing according to ATS/ACCP guidelines, such as: myocardial infarction within the past 6 months, unstable angina, syncope, symptomatic...
The study team makes the final eligibility decision.
Where it's taking place
- Thessaloniki, Exohi, Greece
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, not specified. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Thessaloniki, Exohi, Greece. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.