BridgeMD
Tests treatment safety and results for Periodontitis
Official title This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients
ClinicalTrials.gov ID: NCT07707063
What this study is testing
What is Injectable Platelet-Rich Fibrin (I-PRF)?
Injectable Platelet-Rich Fibrin (I-PRF) is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for periodontitis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is a randomized, controlled, split-mouth clinical trial designed to evaluate and compare the effectiveness of four different subgingival adjuncts used along side standard Scaling and Root Planning (SRP). This protocol is designed to be a standardized therapeutic model.
- Phase 4: studies an already-approved treatment
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Inclusion: Patients with Stage II-IV Periodontitis; at least one bleeding pocket \> 4 mm minimum in every quadrant. Exclusion: patients who:
- Pregnant /Lactating
- History of radiotherapy or chemotherapy in the head/neck region.
- Known hypersensitivity to Iodine or Methylene blue solution
- Systematic antibiotic use within the last 30 days
See the full eligibility criteria
- Inclusion: Patients with Stage II-IV Periodontitis; at least one bleeding pocket \> 4 mm minimum in every quadrant. Exclusion: patients who:
- Pregnant /Lactating
- History of radiotherapy or chemotherapy in the head/neck region.
- Known hypersensitivity to Iodine or Methylene blue solution
- Systematic antibiotic use within the last 30 days
- Long-term use of immunosuppressants or corticosteroids (daily use)
- type 1 / 2 diabetes
The study team makes the final eligibility decision.
Where it's taking place
- Tunis, Mont Fleury, Tunisia
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tunis, Mont Fleury, Tunisia. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.