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New treatment option for End Stage Chronic Renal Failure
Official title The FILTRATE Trial: High-Rate Ultrafiltration for Intravascular Congestion
ClinicalTrials.gov ID: NCT07705269
What this study is testing
- What it's testing
- The purpose of this study is to evaluate whether a personalized, high-rate fluid removal strategy guided by ultrasound is as safe and effective as the standard fluid removal rate for patients with advanced kidney disease who are hospitalized due to severe fluid overload (congestion). When patients with End-Stage Renal Disease (ESRD) on chronic hemodialysis are admitted to the hospital with excess fluid, doctors often need to remove this fluid quickly to relieve symptoms like severe shortness of breath.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Adults over 18 years old with End-Stage Renal Disease on hemodialysis for at least 3 months.
- Admitted to the hospital requiring mechanical fluid removal for acute fluid overload (first in-hospital session).
- Clear ultrasound evidence of severe intravascular congestion (such as diffuse B-lines in the lungs or altered VExUS vascular flow patterns).
- Hemodynamically stable with a baseline blood pressure of at least 120/80 mmHg.
You likely can't join if
- Baseline low blood pressure (\<100/60 mmHg) or active shock (cardiogenic, septic, or distributive).
- Acute coronary syndrome (heart attack), severe heart valve disease, or severe fluid around the heart.
- Known chronic lung disease.
- Pregnancy.
The study team makes the final eligibility decision.
Where it's taking place
- Monterrey, Nuevo León, Mexico
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Monterrey, Nuevo León, Mexico. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.