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New treatment option for Schizophrenia
Official title tACS for Working Memory in Schizophrenia
ClinicalTrials.gov ID: NCT07701343
What this study is testing
- What it's testing
- This study is a randomized, single-blind, sham-controlled crossover trial enrolling 30 schizophrenia patients, each receiving one active and one sham tACS session (7-day washout), targeting P3/P4 at individual alpha frequency (2mA, 30min) during a working memory task, with accuracy and reaction time as primary outcomes, alongside EEG and neurophysiological measures, to test the efficacy and mechanisms of individualized alpha-tACS on working memory.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 50
You may be able to join if
- Aged 18-50 years, meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) diagnostic criteria for schizophrenia...
- Spatial span T-score \<40 on the MATRICS Consensus Cognitive Battery (MCCB).
- Taking 1-2 antipsychotic medications, with stable dosage for at least 1 week prior to enrollment. No use of mood stabilizers, antidepressants, or...
- Impaired functioning in daily activities.
- Willing to participate in this study and provide written informed consent.
You likely can't join if
- Previously diagnosed with or comorbid any other DSM-5 mental disorder besides schizophrenia.
- Presence of significant mood symptoms or substance use disorder (other than caffeine and/or tobacco).
- Presence of any contraindication to transcranial alternating current stimulation (tACS).
- Received other forms of electrical or magnetic stimulation therapy within 1 month prior to enrollment.
- History or current presence of any major physical illness, neurological disorder, or traumatic brain injury that may affect brain structure or...
- Pregnant or breastfeeding women, or women planning to become pregnant during the study period.
The study team makes the final eligibility decision.
Where it's taking place
- Changsha, Hunan, China
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 50 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Changsha, Hunan, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.