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New treatment option for Androgenetic Alopecia (AGA)
Official title Exosome Therapy for Male Androgenetic Alopecia
ClinicalTrials.gov ID: NCT07693244
What this study is testing
What is Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes?
Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes is an investigational medicine, given as an injectable medicine, being studied as a potential treatment for androgenetic alopecia (aga).
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to learn if local scalp injection of human umbilical cord mesenchymal stem cell-derived exosomes (hUCMSC-Exos) can treat androgenetic alopecia (AGA) in male patients with AGA. The main question it aims to answer is: Does hUCMSC-Exos injection improve hair regrowth compared with placebo?
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance. You may not know which one you got.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 55, men only
You may be able to join if
- Participants must meet all of the following criteria to be eligible for enrollment:
- Male people aged 18 to 55 years;
- Diagnosis of androgenetic alopecia classified as Norwood-Hamilton grade III-V;
- Stable pattern of hair loss for at least 6 months prior to screening;
- Willingness to refrain from using any other hair loss treatments during the study period and for 6 months after completion of treatment.
You likely can't join if
- Participants meeting any of the following criteria will be excluded:
- Other types of alopecia, including alopecia areata, cicatricial alopecia, or telogen effluvium;
- Use of minoxidil, finasteride, spironolactone, or other hair growth-related medications within 1 year prior to screening;
- Receipt of platelet-rich plasma (PRP), laser cap therapy, or other scalp procedures within 6 months prior to screening;
- History of autoimmune disease, active scalp infection, coagulation disorders, or malignancy;
- Known hypersensitivity to the investigational product or any of its components;
See the full eligibility criteria
- Participants must meet all of the following criteria to be eligible for enrollment:
- Male people aged 18 to 55 years;
- Diagnosis of androgenetic alopecia classified as Norwood-Hamilton grade III-V;
- Stable pattern of hair loss for at least 6 months prior to screening;
- Willingness to refrain from using any other hair loss treatments during the study period and for 6 months after completion of treatment.
- Participants meeting any of the following criteria will be excluded:
- Other types of alopecia, including alopecia areata, cicatricial alopecia, or telogen effluvium;
- Use of minoxidil, finasteride, spironolactone, or other hair growth-related medications within 1 year prior to screening;
- Receipt of platelet-rich plasma (PRP), laser cap therapy, or other scalp procedures within 6 months prior to screening;
- History of autoimmune disease, active scalp infection, coagulation disorders, or malignancy;
- Known hypersensitivity to the investigational product or any of its components;
- Inability to comply with study procedures, incomplete clinical data, or conditions that may interfere with how well it works evaluation;
- Participation in another clinical trial within the study period;
- Any condition that, in the opinion of the investigator, makes the participant unsuitable for the study.
The study team makes the final eligibility decision.
Where it's taking place
- Beijing, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 55 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Beijing, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.