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Tests treatment safety and results for Endometrial Cancer
Official title DETERMINANTS OF IMMUNOTHERAPY EFFICACY IN ENDOMETRIAL CANCER
ClinicalTrials.gov ID: NCT07690540
What this study is testing
What is Prospective exploratory cohort?
Prospective exploratory cohort is an investigational medicine, being studied as a potential treatment for endometrial cancer.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- In recent years, the introduction of immune checkpoint inhibitors (ICI) in combination with chemotherapy has significantly changed the management of advanced and recurrent Endometrial Cancer (EC). Despite these advances, responses to immunotherapy remain heterogeneous.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older, women only
You may be able to join if
- Age ≥ 18 years
- Histologically confirmed advanced or recurrent endometrial carcinoma or carcinosarcoma
- No prior treatment with immune checkpoint inhibitors
- Availability of paired fresh-frozen and FFPE tumor samples
- Provision of written informed consent for participation in translational research
You likely can't join if
- Refusal or inability to provide informed consent by the patient or legal representative
- Mesenchymal tumors or epithelial tumors of non-endometrial origin (e.g., ovarian cancer)
- Active treatment with immunomodulatory agents at the time of sample collection (e.g., immunotherapy for autoimmune disease)
- Known positivity for HIV, hepatitis B virus (HBV), or hepatitis C virus (HCV)
The study team makes the final eligibility decision.
Where it's taking place
- Milan, Italy, Italy
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Milan, Italy, Italy. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.