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New treatment option for Cholera
Official title Cholera Control by Case-area Targeted Interventions (CATIs)
ClinicalTrials.gov ID: NCT07685574
What this study is testing
What is Cholvax?
Cholvax is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for cholera.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- To evaluate the effectiveness of the CATI approach among household contacts in the reduction of cumulative incidence of cholera and explore the genome analysis and immune response of V. cholerae antigen from different hotspots in Dhaka city, cholera cases will be enrolled by rapid diagnostic test (RDT) from the diarrhoeal patients coming to icddr,b Dhaka hospital.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 1 and older. Healthy volunteers may be eligible.
You may be able to join if
- Index case eligibility
- Some to severe dehydrated diarrheal patient
- Provide signed informed consent form
You likely can't join if
- 1\. Resident in a ward already covered by OCV since 2015 Vaccination Eligibility Inclusion Criteria:
- Aged ≥1 year and non-pregnant
- Meeting the definition of IHC and NHC
- Provide signed informed consent form Exclusion criteria:
- History of taking OCV
- Currently suffering from diarrhea
See the full eligibility criteria
- Index case eligibility
- Some to severe dehydrated diarrheal patient
- Provide signed informed consent form
- 1\. Resident in a ward already covered by OCV since 2015 Vaccination Eligibility Inclusion Criteria:
- Aged ≥1 year and non-pregnant
- Meeting the definition of IHC and NHC
- Provide signed informed consent form Exclusion criteria:
- History of taking OCV
- Currently suffering from diarrhea
- \< 1 year of age
- Pregnant women (verbally confirmed)
- Index case
The study team makes the final eligibility decision.
Where it's taking place
- Dhaka, Bangladesh
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 1 year and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Dhaka, Bangladesh. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.