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New treatment option for Major Depressive Episode (MDE)
Official title Belief Update: The Effects of Depression and Antidepressants in Older People
ClinicalTrials.gov ID: NCT07681492
What this study is testing
- What it's testing
- People in good health do not perceive the future in the same way as those suffering from depression. This difference in perception affects behaviour and emotions and warrants further investigation, both before and after treatment with antidepressants.
- Time commitment: about 12 weeks
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 65 and older. Healthy volunteers may be eligible.
You may be able to join if
- for patients with major depressive disorder :
- Patient over 65 years old in outpatient care
- Patients with major depressive disorder or patients with bipolar major depressive disorder as evaluated by the Mini International Neuropsychiatric...
- Absence of cognitive impairment as evidenced by an MMSE (Mini Mental State Examination) ≥ 24
- MADRS ≥ 20
You likely can't join if
- with major depressive disorder :
- mental disorders other than mood disorders : attention deficit dissorder, borderline personality disorder, schizophrenia, autism spectrum disorder...
- Inability to understand task instructions and perform the behavioral task
- Neurological or neurosurgical comorbidities
- Major visual impairment
- Adults under state medical aid
See the full eligibility criteria
- for patients with major depressive disorder :
- Patient over 65 years old in outpatient care
- Patients with major depressive disorder or patients with bipolar major depressive disorder as evaluated by the Mini International Neuropsychiatric Interview (MINI) semi-structured interview for the group suffering from...
- Absence of cognitive impairment as evidenced by an MMSE (Mini Mental State Examination) ≥ 24
- MADRS ≥ 20
- MMSE ≥ 24
- Change of antidepressants
- Person affiliated with a social security scheme
- Patients who have received informed information about the study and have signed a consent form to participate in the study
- with major depressive disorder :
- mental disorders other than mood disorders : attention deficit dissorder, borderline personality disorder, schizophrenia, autism spectrum disorder, anorexia-bulimia disorder, obsessive-compulsive disorder, anxiety...
- Inability to understand task instructions and perform the behavioral task
- Neurological or neurosurgical comorbidities
- Major visual impairment
- Adults under state medical aid
- Adults under legal protection (legal guardianship, curatorship, trusteeship), persons deprived of their liberty Inclusion Criteria for patients with major depressive disorder :
- Absence of psychiatric disorders attested by administration of the MINI
- Absence of cognitive impairment as evidenced by an MMSE ≥ 24
The study team makes the final eligibility decision.
Where it's taking place
- Rennes, France
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 12 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 65 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Rennes, France. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.