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New treatment option for Intraarticular Injection
Official title Intraarticular Injection of Botox and Hyaluronic Acid in Knee Osteoarthritis
ClinicalTrials.gov ID: NCT07666347
What this study is testing
What is Hyaluronic acid?
Hyaluronic acid is an investigational medicine, given as an once-weekly injectable medicine, being studied as a potential treatment for intraarticular injection.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study aims to compare the efficacy of intra-articular injection of Botulinum toxin and hyaluronic acid on pain in knee osteoarthritis.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 and older
You may be able to join if
- Age ≥ 50 years.
- Both genders.
- Chronic knee osteoarthritis (KOA) according to American College of Rheumatology criteria for the diagnosis of knee osteoarthritis.
- Third or fourth grade Kellgren and Lawrence system for classification of osteoarthritis based on radiological data, it is a common method of...
You likely can't join if
- History of intra-articular injection within the last 6 months,
- History of surgery on the knee joint or major trauma to the lower limb causing fracture.
- Body mass index (BMI) more than 40 kg/m2.
- Medical conditions affecting the joint or lower extremity function such as severe osteoporosis, rheumatoid arthritis, collagen vascular diseases, and...
- Diabetic patient.
- Any contraindication to intra-articular injections for instance immunodeficiency, coagulation defect or anticoagulation therapy taking or skin...
See the full eligibility criteria
- Age ≥ 50 years.
- Both genders.
- Chronic knee osteoarthritis (KOA) according to American College of Rheumatology criteria for the diagnosis of knee osteoarthritis.
- Third or fourth grade Kellgren and Lawrence system for classification of osteoarthritis based on radiological data, it is a common method of classifying the severity of osteoarthritis (OA) using five grades according to...
- History of intra-articular injection within the last 6 months,
- History of surgery on the knee joint or major trauma to the lower limb causing fracture.
- Body mass index (BMI) more than 40 kg/m2.
- Medical conditions affecting the joint or lower extremity function such as severe osteoporosis, rheumatoid arthritis, collagen vascular diseases, and gout.
- Diabetic patient.
- Any contraindication to intra-articular injections for instance immunodeficiency, coagulation defect or anticoagulation therapy taking or skin infection at the site of injection.
- Hypersensitivity to Botulinum toxin or hyaluronic acid.
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, El-Gharbia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 50 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, El-Gharbia, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.