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New treatment option for Atherosclerosis Cardiovascular Disease
Official title Isometric Resistance Exercise on Accelerated Atherosclerosis in Hypertension
ClinicalTrials.gov ID: NCT07665034
What this study is testing
- What it's testing
- Background: Hypertension (HT) is the most common condition worldwide, predisposing to atherosclerotic disease. However, most HT patients have suboptimal BP control despite anti-HT medications.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75. Healthy volunteers may be eligible.
You may be able to join if
- asymptomatic clinically stable adults
- aged 18-75 years
- Both genders
- Suboptimal BP (on stable medication) with SBP 135-160mmHG on ambulatory BP monitoring (AMBP)
- Agreeable to no drug changes in coming 1 year 24 weeks
You likely can't join if
- relative contraindications to AMBP (e.g. atrial fibrillation)
- severe osteoarthritis of knee
- known secondary HT
- pregnancy/breastfeeding
- active malignancy
- Serious coronary profiles, (unstable angina), renal or hepatic derangement
See the full eligibility criteria
- asymptomatic clinically stable adults
- aged 18-75 years
- Both genders
- Suboptimal BP (on stable medication) with SBP 135-160mmHG on ambulatory BP monitoring (AMBP)
- Agreeable to no drug changes in coming 1 year 24 weeks
- Agreeable to provide informed written consent form
- Agreeable to have AMBP and ultrasonic (FMD \& IMT) scan third (baseline, 24 weeks and preferably 1 year)
- relative contraindications to AMBP (e.g. atrial fibrillation)
- severe osteoarthritis of knee
- known secondary HT
- pregnancy/breastfeeding
- active malignancy
- Serious coronary profiles, (unstable angina), renal or hepatic derangement
- Need to change medications for control BP at 24 weeks ( SBP\>160 mmHg)
The study team makes the final eligibility decision.
Where it's taking place
- Shatin, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 75 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Shatin, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.