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New treatment option for Body Temperature Changes
Official title Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain
ClinicalTrials.gov ID: NCT07664462
What this study is testing
- What it's testing
- Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers performing physically demanding work in hot environments. Occupational heat-stress guidelines use work-rest schedules to limit increases in core temperature and physiological strain, but they do not clearly define the safe maximum duration of continuous work before heat-mitigation controls should begin, known as the initial stay time.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 70, men only
You may be able to join if
- Are male.
- Do not smoke or have been smoke free for at least 5 years.
- English or French speaking.
- Ability to provide informed consent.
- Are physically active (engage in exercise at least 2 times per week for ≥30 minutes)
You likely can't join if
- Are regularly exposed to hot environments (e.g., occupational heat exposure)
- Are regularly exposed to hypoxic environments (e.g., high altitudes)
- Experience claustrophobia or discomfort in enclosed environments
- Episode(s) of severe hypoglycemia (requiring the assistance of another person) within the previous year, or inability to sense hypoglycemia...
- Serious complications related to diabetes (gastroparesis, renal disease, uncontrolled hypertension, severe autonomic neuropathy).
- Uncontrolled hypertension - BP \>150 mmHg systolic or \>95 mmHg diastolic in a sitting position.
See the full eligibility criteria
- Are male.
- Do not smoke or have been smoke free for at least 5 years.
- English or French speaking.
- Ability to provide informed consent.
- Are physically active (engage in exercise at least 2 times per week for ≥30 minutes)
- Are regularly exposed to hot environments (e.g., occupational heat exposure)
- Are regularly exposed to hypoxic environments (e.g., high altitudes)
- Experience claustrophobia or discomfort in enclosed environments
- Episode(s) of severe hypoglycemia (requiring the assistance of another person) within the previous year, or inability to sense hypoglycemia (hypoglycemia unawareness).
- Serious complications related to diabetes (gastroparesis, renal disease, uncontrolled hypertension, severe autonomic neuropathy).
- Uncontrolled hypertension - BP \>150 mmHg systolic or \>95 mmHg diastolic in a sitting position.
- Restrictions in physical activity due to disease (e.g. intermittent claudication, renal impairment, active proliferative retinopathy, unstable cardiac or pulmonary disease, disabling stroke, severe arthritis, etc.).
- Use of or changes in medication judged by the patient or investigators to make participation in this study inadvisable.
- Cardiac abnormalities identified during screening
The study team makes the final eligibility decision.
Where it's taking place
- Ottawa, Ontario, Canada
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ottawa, Ontario, Canada. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.