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New treatment option for Parkinson Disease (PD)
Official title Developing Precision Microbiota-Based Cocktail Modification Therapy to Delay the Progression of Parkinson's Disease (PD) - Use Preclinical Human Trials to Confirm the Impact of the Optimal "Probiotic Y7, Tryptophan and Branched-chain Amino Acid" Cocktail Formula on Early Stage PD Patients
ClinicalTrials.gov ID: NCT07619560
What this study is testing
- What it's testing
- Preclinical human trials will be utilized to validate the research direction, followed by clinical trials to assess the impact of a cocktail formula product containing the optimal probiotic Y7 combined metabolites on motor, cognitive, and non-motor functions in early Parkinson's disease patients. The study aims to recruit 120 patients (stage 1-3) and employ a two-arm, randomized controlled trial (RCT) design, dividing subjects into intervention and control groups for a 12 weeks trial period.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 30 to 85
You may be able to join if
- Subject
- Age between 30-85 years old.
- Diagnosed with early-stage Parkinson's disease (Hoehn and Yahr scale stage 1-3).
- Brain MRI confirms striatal degeneration in the basal ganglia region, with no history of stroke.
- Responds to Parkinson's disease-related medications (e.g., Levodopa).
You likely can't join if
- Unable to complete interviews or has mobility issues.
- Presence of major or acute illness before or during the study.
- Co-existing intestinal co-infections, such as CDI, E. coli, Salmonella, Shigella, Campylobacter, plague, or cytomegalovirus.
- Allergic to the intervention product.
- Pregnant or breastfeeding women.
See the full eligibility criteria
- Subject
- Age between 30-85 years old.
- Diagnosed with early-stage Parkinson's disease (Hoehn and Yahr scale stage 1-3).
- Brain MRI confirms striatal degeneration in the basal ganglia region, with no history of stroke.
- Responds to Parkinson's disease-related medications (e.g., Levodopa).
- Free of any major or acute illnesses.
- Able to comply with the 12 weeks intervention and required assessments for the study.
- Unable to complete interviews or has mobility issues.
- Presence of major or acute illness before or during the study.
- Co-existing intestinal co-infections, such as CDI, E. coli, Salmonella, Shigella, Campylobacter, plague, or cytomegalovirus.
- Allergic to the intervention product.
- Pregnant or breastfeeding women.
The study team makes the final eligibility decision.
Where it's taking place
- Taipei, Taiwan
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 30 years to 85 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Taipei, Taiwan. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.