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Compares treatment options for Distal Ureteral Stone
Official title L-Citrulline Versus Tamsulosin for Medical Expulsive Therapy of Distal Ureteral Stones
ClinicalTrials.gov ID: NCT07617909
What this study is testing
What is L-Citrulline?
L-Citrulline is an investigational medicine, given as an once-weekly pill taken by mouth, being studied as a potential treatment for distal ureteral stone.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study will compare L-citrulline and tamsulosin as medical expulsive therapy for adults with single distal ureteral stones. Eligible participants with a single distal ureteral stone measuring 5 to 10 mm will be randomly assigned to receive either oral L-citrulline 750 mg twice daily or oral tamsulosin 0.4 mg once daily.
- Phase 2: a mid-size study of how well it works
- Time commitment: about 4 weeks
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60
You may be able to join if
- Adults aged 18 to 60 years.
- Single distal ureteral stone.
- Stone size 5 to 10 mm.
- Normal renal function.
- Controlled pain.
You likely can't join if
- Fever or active urinary tract infection.
- Severe hydronephrosis.
- Solitary kidney.
- Pregnancy.
- Previous ureteric surgery.
- Multiple ureteral stones.
See the full eligibility criteria
- Adults aged 18 to 60 years.
- Single distal ureteral stone.
- Stone size 5 to 10 mm.
- Normal renal function.
- Controlled pain.
- Willingness to comply with follow-up for 4 weeks.
- Written informed consent.
- Fever or active urinary tract infection.
- Severe hydronephrosis.
- Solitary kidney.
- Pregnancy.
- Previous ureteric surgery.
- Multiple ureteral stones.
- Indication for urgent surgical intervention.
- Known hypersensitivity or contraindication to L-citrulline or tamsulosin.
- Inability to complete follow-up.
The study team makes the final eligibility decision.
Where it's taking place
- Banī Suwayf, Beni Suweif Governorate, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 4 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Banī Suwayf, Beni Suweif Governorate, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.