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New treatment option for Postoperative Pain After Thoracic Surgery
Official title Comparison of IV Analgesia Protocols After the Regional Block's Effect Diminishes in Thoracic Surgery
ClinicalTrials.gov ID: NCT07610408
What this study is testing
What is Fentanyl IV PCA?
Fentanyl IV PCA is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for postoperative pain after thoracic surgery.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The purpose of this study is to compare the effectiveness of three different intravenous (IV) patient-controlled analgesia (PCA) regimens-Fentanyl, Tramadol, and Ibuprofen-in managing postoperative pain and respiratory performance in patients undergoing Video-Assisted Thoracoscopic Surgery (VATS). While regional blocks like Erector Spinae Plane (ESP) block provide effective early analgesia, their effect typically diminishes after 8-12 hours, leading to potential 'rebound pain.' This study specifically investigates the period following the duration of the regional block's action.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- \- Patients aged 18 to 80 years.
- \- ASA (American Society of Anesthesiologists) Physical Status Score of I-III.
- \- Body Mass Index (BMI) between 18 and 35 kg/m².
- \- Undergoing elective thoracic surgery via Video-Assisted Thoracoscopic Surgery (VATS).
- \- Voluntary participation confirmed by signing the written Informed Consent Form.
You likely can't join if
- \- Age below 18 or above 80 years.
- \- Advanced organ failure (e.g., severe hepatic or renal impairment).
- \- ASA physical status \> III.
- \- History of chronic pain treatment or long-term opioid use.
- \- BMI \ 35 kg/m².
- \- Pregnancy or breastfeeding.
See the full eligibility criteria
- \- Patients aged 18 to 80 years.
- \- ASA (American Society of Anesthesiologists) Physical Status Score of I-III.
- \- Body Mass Index (BMI) between 18 and 35 kg/m².
- \- Undergoing elective thoracic surgery via Video-Assisted Thoracoscopic Surgery (VATS).
- \- Voluntary participation confirmed by signing the written Informed Consent Form.
- \- Age below 18 or above 80 years.
- \- Advanced organ failure (e.g., severe hepatic or renal impairment).
- \- ASA physical status \> III.
- \- History of chronic pain treatment or long-term opioid use.
- \- BMI \ 35 kg/m².
- \- Pregnancy or breastfeeding.
- \- Limited cooperation due to dementia or uncontrolled psychiatric disorders.
- \- Communication barriers (inability to communicate in the native language).
- \- History of substance or drug abuse.
- \- Known allergy or contraindication to the study drugs (Fentanyl, Tramadol, or Ibuprofen).
- \- Contraindication to regional block placement (e.g., infection at the injection site).
The study team makes the final eligibility decision.
Where it's taking place
- Ankara, Keçiören, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ankara, Keçiören, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.