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New treatment option for Sleep
Official title Sleep and Performance
ClinicalTrials.gov ID: NCT07608614
What this study is testing
- What it's testing
- This research is being done to apply new, contrast-free MRI (Magnetic Resonance Imaging) methods to understand the brain's waste clearance system (the "glymphatic" system) in younger adults. The Investigators hope the study will show how the different brain regions are involved in maintaining memories and how poor sleep affects these regions and our ability to remember.
- Time commitment: about 4 weeks
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 30. Healthy volunteers may be eligible.
You may be able to join if
- Physically and psychologically healthy
- Good habitual sleep between 6 and 10 hours in duration, as assessed by questionnaire and pre-study week sleep/wake diary
- Regular bedtimes, habitually getting up between 05:00 and 09:00, as assessed by questionnaire and pre-study week sleep/wake diary
You likely can't join if
- people who have any type of non-MRI compatible bioimplant activated by mechanical, electronic, or magnetic means (e.g., cochlear implants...
- people who have any type of ferromagnetic bioimplant that could potentially be displaced.
- people who have cerebral aneurysm
- people who may have shrapnel imbedded in their bodies (such as from war wounds), metal workers and machinists (potential for metallic fragments in or...
- Minors (younger than 18 years)
- Pregnant women ( Participants of childbearing potential will receive a urine pregnancy test. If the test is positive, the participant will be...
See the full eligibility criteria
- Physically and psychologically healthy
- Good habitual sleep between 6 and 10 hours in duration, as assessed by questionnaire and pre-study week sleep/wake diary
- Regular bedtimes, habitually getting up between 05:00 and 09:00, as assessed by questionnaire and pre-study week sleep/wake diary
- people who have any type of non-MRI compatible bioimplant activated by mechanical, electronic, or magnetic means (e.g., cochlear implants, pacemakers, neurostimulators, biostimulators, electronic infusion pumps, etc.)...
- people who have any type of ferromagnetic bioimplant that could potentially be displaced.
- people who have cerebral aneurysm
- people who may have shrapnel imbedded in their bodies (such as from war wounds), metal workers and machinists (potential for metallic fragments in or near the eyes).
- Minors (younger than 18 years)
- Pregnant women ( Participants of childbearing potential will receive a urine pregnancy test. If the test is positive, the participant will be excluded)
- Breastfeeding
- people who cannot adhere to the experimental protocols for any reason, or have an inability to communicate with the researcher.
- no clinical disorders and/or illnesses, no psychiatric illnesses), as assessed by history and questionnaires
- no alcohol during study and no normal excessive alcohol consumption assessed by questionnaire
- No history of drug or alcohol abuse in the past year and no history of methamphetamine abuse, as assessed by questionnaires.
- Not a dependent smoker or vaper, and not morning dependent on tobacco, nicotine, or cannabis, as assessed by questionnaire.
- No history of moderate to severe brain injury, as assessed by questionnaire
- No anti-psychotic medication for ADHD/ADD, as assessed by questionnaire
- No previous adverse reaction to sleep deprivation, as assessed by questionnaire
- Not vision-impaired unless corrected back to normal.
- Not hearing impaired unless corrected to normal, as assessed by questionnaire
- Not pregnant, as assessed by history and questionnaire
- No sleep or circadian disorder, as assessed by questionnaires
- No use of melatonin within 1 week of study enrollment
- No travel across more than one time zone within one month of entering the study and no crossing times zones during study participation, as assessed by questionnaire.
- No shift work within three months of entering the study and no shift work during duration study participation, as assessed by questionnaire.
- epilepsy
The study team makes the final eligibility decision.
Where it's taking place
- Seattle, Washington, United States
Compensation & support
Compensation mentioned.
ClinicalTrials.gov doesn't provide a reliable structured field for payment or travel support - confirm details with the study team.
Questions & answers
Do participants get paid in this trial?
This study's listing includes signals that participants may be compensated or receive a stipend. Amounts vary and are set by the study team - confirm the details with them.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The study runs about 4 weeks per participant, based on its public description. The team confirms the exact schedule and number of visits before you enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 30 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Seattle, Washington, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.