BridgeMD
New treatment option for Unilateral Lower Limb Suspension (Simulated Microgravity)
Official title Unloaded Minds - How Prolonged Unloading Shapes Human Performance in Lunar Gravity
ClinicalTrials.gov ID: NCT07607340
What this study is testing
- What it's testing
- During spaceflight and lunar missions, reduced gravitational loading causes the muscles and nervous system to decondition rapidly. While muscle wasting is well documented, much less is known about how the brain and spinal cord adapt to the absence of normal mechanical loading - and how these central changes interact with muscle deterioration to impair movement control.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 60. Healthy volunteers may be eligible.
You may be able to join if
- \- 18-60 years of age, willing to participate
You likely can't join if
- high activity level according to the GLTEQ
- contraindications to exercise
- pregnancy
- contraindications to MRI
- active cardiovascular disease
- cerebrovascular disease including previous stroke
See the full eligibility criteria
- \- 18-60 years of age, willing to participate
- high activity level according to the GLTEQ
- contraindications to exercise
- pregnancy
- contraindications to MRI
- active cardiovascular disease
- cerebrovascular disease including previous stroke
- aneurysm (large vessels or intracranial)
- pulmonary disease including pulmonary hypertension or COPD
- metabolic diseases (including: hyper/hypoparathyroidism, hyper/hypothyroidism, Cushing's disease, type 1 or type 2 diabetes)
- active inflammatory bowel disease
- kidney disease
- malignancy
- recent steroid treatment (within the past 6 months), or hormone replacement therapy
- coagulation disorders
- musculoskeletal or neurological diseases
- diseases requiring long-term medication, including statin therapy
- smoking
The study team makes the final eligibility decision.
Where it's taking place
- Huddinge, Stockholm County, Sweden
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 60 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Huddinge, Stockholm County, Sweden. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.