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New treatment option for Endometriosis
Official title Whole-Body Cryotherapy as a Non-Pharmacological Treatment to Reduce Chronic Pelvic Pain and Improve Quality of Life in People With Endometriosis
ClinicalTrials.gov ID: NCT07603960
What this study is testing
- What it's testing
- The aim of this study is to investigate whether whole-body cryotherapy (a brief exposure to very cold temperatures) can help reduce pain and improve quality of life in people living with endometriosis, and whether it may represent a safe, non-pharmacological approach to managing endometriosis-related symptoms. Up to 30 participants with symptomatic endometriosis (chronic pelvic pain for more than six months) will be recruited over a 12-month period.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 16 and older, women only
You may be able to join if
- Women or assigned female at birth
- Aged 16 or over
- Endometriosis identified at laparoscopy or imaging, performed within the last ten years
- Chronic pelvic pain for more than six months
- Willing to comply with the treatment
You likely can't join if
- Pregnant, breastfeeding or actively trying to get pregnant
- Post-menopausal (no periods for \>12 months and not taking hormonal treatments to prevent periods, or bilateral oophorectomy performed)
- Previous hysterectomy with bilateral oophorectomy
- Raynaud's Disease
- Current treatment for malignancy
- Diabetes
See the full eligibility criteria
- Women or assigned female at birth
- Aged 16 or over
- Endometriosis identified at laparoscopy or imaging, performed within the last ten years
- Chronic pelvic pain for more than six months
- Willing to comply with the treatment
- Willing to use effective contraception throughout the trial (if needed)
- Willing and able to give informed consent
- Pregnant, breastfeeding or actively trying to get pregnant
- Post-menopausal (no periods for \>12 months and not taking hormonal treatments to prevent periods, or bilateral oophorectomy performed)
- Previous hysterectomy with bilateral oophorectomy
- Raynaud's Disease
- Current treatment for malignancy
- Diabetes
- Known hypothyroidism
- Pre-existing or current diagnosis of anaemia
- Cardiovascular disease: severe hypertension (180/100, unstable angina, arrhythmia, recent (\<6months) myocardial infarction, peripheral artery disease, cardiac pacemaker, recent (\<6months) stroke or transient ischaemic...
- Acute kidney and urinary tract diseases
- Cryoglobulinemia
- Previous venous thromboembolism or peripheral artery occlusive disease
- Cold urticaria
- Livedo reticularis
- Open wounds or ulcers, large-area bacterial and viral skin infections
- Uncontrolled seizure disorder
- Known coagulopathy (eg von Willibrand disease, haemophilia)
- Severe claustrophobia
- Acute infections and fever
- Intoxication (alcohol, drugs)
- Signs or symptoms of cold allergy
- Severe wasting diseases
- Known Hepatitis B/C and/or HIV (due to Royal Mail restrictions on biospecimen postage)
The study team makes the final eligibility decision.
Where it's taking place
- Edinburgh, Scotland, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 16 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Edinburgh, Scotland, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.