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New treatment option for Chemotherapy Induced Peripheral Neuropathy
Official title Self-applied taVNS for CIPN
ClinicalTrials.gov ID: NCT07596030
What this study is testing
- What it's testing
- The purpose of this study is to determine the feasibility of using a portable device at home to self-administer transcutaneous auricular vagus nerve stimulation (taVNS). This handheld device has two small electrodes that are placed on specific areas of the outer ear.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 80
You may be able to join if
- Chemotherapy-induced peripheral neuropathy (CIPN) group:
- Age 18-80 years
- Prior exposure to platinum or taxane chemotherapy
- Glove/stocking dysesthesias ≥3 months that began after neurotoxic chemotherapy
- Worst CIPN-related pain ≥4/10 over the last week Registry Cohort:
You likely can't join if
- All participants:
- Unstable cardiac disease/ Known arrhythmias
- Head or neck cancer or metastases
- Recent ear trauma or active dermatologic disease at the stimulation site
- \<2 months since completion of cancer treatment or surgery
- Metal implants in the head or neck (e.g., cochlear implant)
See the full eligibility criteria
- Chemotherapy-induced peripheral neuropathy (CIPN) group:
- Age 18-80 years
- Prior exposure to platinum or taxane chemotherapy
- Glove/stocking dysesthesias ≥3 months that began after neurotoxic chemotherapy
- Worst CIPN-related pain ≥4/10 over the last week Registry Cohort:
- Age 18-80 years
- Prior exposure to platinum or taxane chemotherapy
- Denis any current neuropathic symptoms as described above.
- All participants:
- Unstable cardiac disease/ Known arrhythmias
- Head or neck cancer or metastases
- Recent ear trauma or active dermatologic disease at the stimulation site
- \<2 months since completion of cancer treatment or surgery
- Metal implants in the head or neck (e.g., cochlear implant)
- Implanted electronic devices (e.g., pacemaker)
- Known allergy to tape/adhesives
- History of seizure/epilepsy, intracranial pathology, or skull defect
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Coral Gables, Florida, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 80 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Coral Gables, Florida, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.