BridgeMD
New treatment option for Food Allergy in Children
Official title Pathway to Peanut Tolerance
ClinicalTrials.gov ID: NCT07592780
What this study is testing
- What it's testing
- While rigorous clinical trials have established peanut OIT as a promising therapy capable of inducing desensitization and even remission, its transition to routine clinical practice requires robust real-world evidence. Current management relies on strict avoidance, and the lack of reliable biomarkers to predict long-term success remains a significant barrier to the wider, more accessible application of OIT.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 2 to 17
You may be able to join if
- Subject's parent and/ or guardian must be able to understand and provide informed consent.
- Age 2 to 17 years of age
- Either sex
- Any race, any ethnicity
- Have a history of sensitization [positive skin prick test to peanut extract as defined by wheal size at least 3mm above control OR peanut-specific...
You likely can't join if
- Individuals who meet any of these criteria are not eligible for enrolment:
- Any disorder in which adrenaline is contraindicated (such as hypertension or cardiac rhythm disorders)
- History of chronic diseases requiring therapy (other than asthma, atopic dermatitis, allergic rhinitis)
- Past or current major illness that in the opinion of the Site investigator may affect the subject's ability to participate in the study e.g...
- Concurrent treatment with any allergen immunotherapy
- Participation in any trials of therapeutic interventions for FA, or therapy with anti-IgE or other biologics within 1 year of enrolment
See the full eligibility criteria
- Subject's parent and/ or guardian must be able to understand and provide informed consent.
- Age 2 to 17 years of age
- Either sex
- Any race, any ethnicity
- Have a history of sensitization [positive skin prick test to peanut extract as defined by wheal size at least 3mm above control OR peanut-specific IgE ≥0.35 kUA/L]
- Individuals who meet any of these criteria are not eligible for enrolment:
- Any disorder in which adrenaline is contraindicated (such as hypertension or cardiac rhythm disorders)
- History of chronic diseases requiring therapy (other than asthma, atopic dermatitis, allergic rhinitis)
- Past or current major illness that in the opinion of the Site investigator may affect the subject's ability to participate in the study e.g. increased risk to the participant
- Concurrent treatment with any allergen immunotherapy
- Participation in any trials of therapeutic interventions for FA, or therapy with anti-IgE or other biologics within 1 year of enrolment
- Current uncontrolled or moderate to severe asthma as defined by FEV1 value \<80% predicted for participants aged 7 years or older and are able to perform spirometry
- Gastrointestinal eosinophilic disorders
- Use of short-acting antihistamine (e.g. chlorpheniramine) within 3 days prior to open-labelled food challenge or skin testing, or medium-acting antihistamine (e.g. cetirizine, loratadine) within 5 days prior to...
- Use of beta-blockers, ACE inhibitors, angiotensin-receptor blockers or calcium channel blockers
The study team makes the final eligibility decision.
Where it's taking place
- Hong Kong, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 2 years to 17 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hong Kong, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.