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New treatment option for Spinal Cord Injuries (SCI)
Official title Spasticity in SCI Following Acute Intermittent Hypoxia
ClinicalTrials.gov ID: NCT07583498
What this study is testing
- What it's testing
- This study aims to observe the effects of administration of a breathing intervention (Acute Intermittent Hypoxia (AIH)) on spasticity (tightness) in individuals with incomplete Spinal Cord Injury. It is hypothesized that hypoxia will decrease the reflex threshold of the biceps brachii, indicating an increase in spasticity following the AIH.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age \>= 18
- Non-progressive spinal Cord injury at least 6 months prior
- Level of injury between C1-C8
- ISNCSCI ASIA classification C or D
- Measurable Spasticity
You likely can't join if
- Pre-existing hypoxic pulmonary disease
- Positive Covid-Pneumonia diagnosis within 1 year of visit
- Uncontrolled hypertension \>140/90 mmHg
- Individuals who are currently pregnant/nursing or planning on becoming pregnant
- Individuals with a tracheostomy or who utilize mechanical ventilation
- A botulinum toxin injection to upper extremity musculature within the past 3 months
See the full eligibility criteria
- Age \>= 18
- Non-progressive spinal Cord injury at least 6 months prior
- Level of injury between C1-C8
- ISNCSCI ASIA classification C or D
- Measurable Spasticity
- Pre-existing hypoxic pulmonary disease
- Positive Covid-Pneumonia diagnosis within 1 year of visit
- Uncontrolled hypertension \>140/90 mmHg
- Individuals who are currently pregnant/nursing or planning on becoming pregnant
- Individuals with a tracheostomy or who utilize mechanical ventilation
- A botulinum toxin injection to upper extremity musculature within the past 3 months
- Currently taking Baclofen
- Congestive Heart Failure
- Cardiac arrhythmias
- Uncontrolled diabetes mellitus
- Chronic obstructive pulmonary disease
- Emphysema
- Severe Asthma
- Previous myocardial infarction
- Carotid/intracerebral artery stenosis
- Orthopedic injuries or surgeries that impact the ability to use the upper extremity
- History of Epilepsy
The study team makes the final eligibility decision.
Where it's taking place
- Chicago, Illinois, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chicago, Illinois, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.