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New treatment option for Overweight
Official title A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
ClinicalTrials.gov ID: NCT07575932
What this study is testing
What is PF-08653945?
PF-08653945 is an investigational medicine, given as an injection under the skin, being studied as a potential treatment for overweight.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is being done to learn about the safety and effects of the study drugs, PF-08653945 and PF-08653944, when given alone or together for weight loss, compared to a placebo (a dummy drug that has no active ingredient in it).
- Phase 2: a mid-size study of how well it works
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Eligible participants for this study include:
- adults aged 18 years or older with
- obesity (BMI of 30.0 kg/m2 to 50.0 kg/m2) or with
- overweight (BMI of 27.0 kg/m2 to \<30.0 kg/m2) who also have at least 1 prespecified weight-related comorbidity (hypertension, dyslipidemia...
You likely can't join if
- Participants who are not eligible include those with diabetes mellitus, a body weight change of \>5% or use of weight loss medications in the 12...
The study team makes the final eligibility decision.
Where it's taking place
- Chandler, Arizona, United States
- Sun City West, Arizona, United States
- Tucson, Arizona, United States
- Canoga Park, California, United States
- Fountain Valley, California, United States
- Garden Grove, California, United States
- Lomita, California, United States
- Long Beach, California, United States
- Los Alamitos, California, United States
- Modesto, California, United States
- San Diego, California, United States
- Tustin, California, United States
- Walnut Creek, California, United States
- Hialeah, Florida, United States
- Jacksonville, Florida, United States
- Miami, Florida, United States
- Orlando, Florida, United States
- Atlanta, Georgia, United States
- Stockbridge, Georgia, United States
- Morton, Illinois, United States
+ 39 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Chandler, Arizona, United States; Sun City West, Arizona, United States; Tucson, Arizona, United States; Canoga Park, California, United States; Fountain Valley, California, United States; Garden Grove, California, United States and 53 more location(s). Enter your location above to see the nearest site and check your eligibility.
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BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.