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New treatment option for Post-menopause
Official title Beetroot Juice: a Natural Aid for Boosting the Health Benefits of Exercise in Post-menopausal Women?
ClinicalTrials.gov ID: NCT07572877
What this study is testing
- What it's testing
- Menopause and ageing bring several changes to women's health, partly due to a decline in the hormone estrogen. This reduction affects multiple systems in the body, including muscles and bones, and also influences the production of nitric oxide, a molecule that plays a key role in regulating blood flow and blood pressure.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 70, women only
You may be able to join if
- Self-reported biological female and postmenopausal (≥12 months of amenorrhea)
- Aged 50-70 years
- Body mass index (BMI) 25-39.9 kg/m²
- No contraindications to exercise
- Physically inactive (\<150 minutes/week of moderate-intensity activity)
You likely can't join if
- Known allergy to nitrates or beetroot juice
- Current smoker or use of nicotine/tobacco products
- Resting blood pressure \<90/60 mmHg
- Hypertension greater than stage II (≥160/100 mmHg, ESH criteria)
- Use of prescription medications affecting heart rate (e.g., systemic β-adrenergic blockers) or nitrate availability (e.g., nitrates, proton pump...
- History of cardiovascular disease (e.g., myocardial infarction, stroke, ischemic heart disease, peripheral artery disease, valvular disease, or...
See the full eligibility criteria
- Self-reported biological female and postmenopausal (≥12 months of amenorrhea)
- Aged 50-70 years
- Body mass index (BMI) 25-39.9 kg/m²
- No contraindications to exercise
- Physically inactive (\<150 minutes/week of moderate-intensity activity)
- Able to walk on a treadmill and ambulate without limitations
- Adequate proficiency in Norwegian to complete questionnaires
- Willingness and ability to comply with the study schedule and visits
- Known allergy to nitrates or beetroot juice
- Current smoker or use of nicotine/tobacco products
- Resting blood pressure \<90/60 mmHg
- Hypertension greater than stage II (≥160/100 mmHg, ESH criteria)
- Use of prescription medications affecting heart rate (e.g., systemic β-adrenergic blockers) or nitrate availability (e.g., nitrates, proton pump inhibitors)
- History of cardiovascular disease (e.g., myocardial infarction, stroke, ischemic heart disease, peripheral artery disease, valvular disease, or aortic aneurysm)
- Symptoms suggestive of heart disease (e.g., chest pain or dyspnea)
- Major metabolic disease (e.g., type 1 or type 2 diabetes) or thyroid disorders
- Recent cancer diagnosis or treatment (within the past 5 years)
- Significant orthopedic limitations or other contraindications to exercise
- Diagnosed cognitive impairment
- Planned travel or elective surgery that would interfere with adherence to the intervention
- Psychological or social factors that may interfere with study participation
- Residing beyond a reasonable distance from the study site (logistical constraints)
The study team makes the final eligibility decision.
Where it's taking place
- Bergen, Norway
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 50 years to 70 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Bergen, Norway. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.