Recruiting NA Androgenetic Alopecia

New treatment option for Androgenetic Alopecia

Official title JAK2 Expression in Androgenetic Alopecia Before and After Topical Minoxidil

ClinicalTrials.gov ID: NCT07563036

What this study is testing

What is Topical Minoxidil 5% Solution?

Topical Minoxidil 5% Solution is an investigational medicine, given as an once-daily treatment applied to the skin, being studied as a potential treatment for androgenetic alopecia.

Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.

What it's testing
Androgenetic alopecia is a common form of progressive hair loss. This prospective single-arm pre-post interventional study aims to assess tissue Janus Kinase 2 (JAK2) expression in patients with androgenetic alopecia by comparing balding and non-balding scalp at baseline, and to evaluate changes in JAK2 expression in balding scalp after 3 months of topical minoxidil 5% therapy.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 50, men only. Healthy volunteers may be eligible.

You may be able to join if

  • Male adults aged 18 to 50 years with androgenetic alopecia.
  • Mild to moderate disease severity, defined as Hamilton-Norwood scale II to V.
  • Patients who are treatment-naive or willing to undergo an adequate washout period for prior hair loss therapies of at least 1 month.
  • Willing and able to provide written informed consent.

You likely can't join if

  • Other types of hair loss, including inflammatory or scarring alopecia.
  • Inflammatory scalp dermatoses, such as psoriasis or seborrheic dermatitis.
  • Use of systemic immunosuppressants, JAK inhibitors, or systemic corticosteroids within the last 12 months.
  • History of severe systemic disease, including renal, cardiovascular, or hepatic disease.
  • Chemotherapy during the last 5 years.
  • Bleeding disorders.

The study team makes the final eligibility decision.

Where it's taking place

  • Cairo, Cairo Governorate, Egypt

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling male, 18 years to 50 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Cairo, Cairo Governorate, Egypt. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.