BridgeMD
New treatment option for Carotid Artery Stenosis Symptomatic
Official title Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
ClinicalTrials.gov ID: NCT07556887
What this study is testing
- What it's testing
- Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated with surgery or stenting to remove the plaque.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Mentally competent
- 18 years or older
- Recent (\<30 days) stroke (modified Rankin scale ≤3) or TIA
- Ipsilateral 30-99% atheromatous stenosis at the carotid bifurcation assessed using non-invasive imaging according to NASCET criteria
- Life expectancy \>5 years
You likely can't join if
- Cardiac source of embolism
- Carotid stenosis caused by non-atherosclerotic disease e.g. dissection, fibromuscular disease or neck radiotherapy.
- MRI contra-indications
- Pregnancy
See the full eligibility criteria
- Mentally competent
- 18 years or older
- Recent (\<30 days) stroke (modified Rankin scale ≤3) or TIA
- Ipsilateral 30-99% atheromatous stenosis at the carotid bifurcation assessed using non-invasive imaging according to NASCET criteria
- Life expectancy \>5 years
- Patient and stenosis are suitable for carotid revascularisation
- Patient is agreeable to randomisation and willing to accept either IMPROVE-based or CAU-based selection method for carotid revascularisation
- Cardiac source of embolism
- Carotid stenosis caused by non-atherosclerotic disease e.g. dissection, fibromuscular disease or neck radiotherapy.
- MRI contra-indications
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Arnhem, Gelderland, Netherlands
- Nijmegen, Gelderland, Netherlands
- Heerlen, Limburg, Netherlands
- Maastricht, Limburg, Netherlands
- Amsterdam, North Holland, Netherlands
- Zwolle, Overijssel, Netherlands
- Dordrecht, South Holland, Netherlands
- Rotterdam, South Holland, Netherlands
- The Hague, South Holland, Netherlands
- Utrecht, Utrecht, Netherlands
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Arnhem, Gelderland, Netherlands; Nijmegen, Gelderland, Netherlands; Heerlen, Limburg, Netherlands; Maastricht, Limburg, Netherlands; Amsterdam, North Holland, Netherlands; Zwolle, Overijssel, Netherlands and 4 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.