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New treatment option for Transcatheter Aortic Valve Replacement (TAVR)
Official title Patient Quality of Recovery After TAVR With Different Sedation Regimens
ClinicalTrials.gov ID: NCT07556523
What this study is testing
What is Propofol?
Propofol is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for transcatheter aortic valve replacement (tavr).
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to learn whether the type of sedation medication used during a transcatheter aortic valve replacement (TAVR) affects how people recover after the procedure. The main question this study aims to answer is whether different sedation regimens (propofol, dexmedetomidine, or midazolam with fentanyl) lead to differences in quality of recovery on the first day after the procedure.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 90
You may be able to join if
- 18-90 years old, inclusive
- Undergoing transfemoral TAVR under Monitored Anesthesia Care (MAC)
- Speaks English or Spanish
- Consents to participate
You likely can't join if
- Preoperative heart rate \< 50 bpm or arrhythmias (e.g., AFib with RVR)
- Conduction abnormalities (e.g., 2nd/3rd degree AV block without pacer)
- Allergy or contraindication to study drugs
- Pulmonary artery pressure \> 70mmHg
- Morbid obesity BMI \> 50
- Pregnancy
See the full eligibility criteria
- 18-90 years old, inclusive
- Undergoing transfemoral TAVR under Monitored Anesthesia Care (MAC)
- Speaks English or Spanish
- Consents to participate
- Preoperative heart rate \< 50 bpm or arrhythmias (e.g., AFib with RVR)
- Conduction abnormalities (e.g., 2nd/3rd degree AV block without pacer)
- Allergy or contraindication to study drugs
- Pulmonary artery pressure \> 70mmHg
- Morbid obesity BMI \> 50
- Pregnancy
- Unable to consent in English or Spanish
The study team makes the final eligibility decision.
Where it's taking place
- Glenview, Illinois, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Glenview, Illinois, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.