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Compares treatment options for Lower Extremity
Official title Bupivacaine-Lidocaine vs Bupivacaine for Ultrasound-Guided Popliteal Sciatic Nerve Block
ClinicalTrials.gov ID: NCT07550348
What this study is testing
What is Bupivacaine-Lidocaine Combination?
Bupivacaine-Lidocaine Combination is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for lower extremity.
Also referred to as Lidocaine 2% + Bupivacaine 0.5%.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This prospective, randomized, double-blind clinical trial aims to compare the efficacy of two local anesthetic regimens for ultrasound-guided popliteal sciatic nerve block in adult patients undergoing elective distal lower extremity surgery. Eligible participants (ages 18-65, ASA physical status I-III, BMI 18-35 kg/m²) will be randomized into two equal groups of 30.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65
You may be able to join if
- Age between 18 and 65 years
- American Society of Anesthesiologists (ASA) physical status classification I, II, or III
- Scheduled for elective distal lower extremity surgery (below-knee)
- Body mass index (BMI) between 18 and 35 kg/m²
- Provision of written informed consent
You likely can't join if
- Refusal to participate in the study
- Morbid obesity (BMI ≥35 kg/m²)
- Known allergy or hypersensitivity to any local anesthetic agent
- Severe cardiac, hepatic, or renal disease
- Pre-existing neurological deficits or peripheral neuropathy
- Use of anticoagulant therapy
See the full eligibility criteria
- Age between 18 and 65 years
- American Society of Anesthesiologists (ASA) physical status classification I, II, or III
- Scheduled for elective distal lower extremity surgery (below-knee)
- Body mass index (BMI) between 18 and 35 kg/m²
- Provision of written informed consent
- Refusal to participate in the study
- Morbid obesity (BMI ≥35 kg/m²)
- Known allergy or hypersensitivity to any local anesthetic agent
- Severe cardiac, hepatic, or renal disease
- Pre-existing neurological deficits or peripheral neuropathy
- Use of anticoagulant therapy
- History of prior surgery or significant scar tissue in the popliteal fossa
- Pregnancy
- Chronic opioid use at home
The study team makes the final eligibility decision.
Where it's taking place
- Erzurum, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Erzurum, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.