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Compares treatment options for Surgical Blood Loss
Official title PVI vs ESP Block for Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery.
ClinicalTrials.gov ID: NCT07550114
What this study is testing
- What it's testing
- This randomized controlled trial compares periarticular vasoconstrictor infiltration (PVI) versus erector spinae plane block (ESP) to reduce bleeding and postoperative pain in adults undergoing lumbar fusion surgery (up to 3 levels). Patients are randomly assigned 1:1 to receive ultrasound-guided ropivacaine 0.2% + epinephrine 1:200,000: PVI (150-200mL bilateral in retrolaminar, thoracolumbar fascia, supraspinous ligament, subcutaneous planes) or ESP (20mL/side at transverse processes).
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- More than 18 years old.
- ASA I-III
- Scheduled primary spinal instrumentation surgery (lumbar/thoracolumbar fusion)
- Signed informed consent
You likely can't join if
- Allergy/contraindication to study drugs (ropivacaine, epinephrine)
- Coagulopathy.
- Infection at block site
- Neuromuscular disease affecting evaluation.
- Chronic opioid use (\>30mg morphine equivalents/day)
- Cognitive impairment preventing pain reporting.
See the full eligibility criteria
- More than 18 years old.
- ASA I-III
- Scheduled primary spinal instrumentation surgery (lumbar/thoracolumbar fusion)
- Signed informed consent
- Allergy/contraindication to study drugs (ropivacaine, epinephrine)
- Coagulopathy.
- Infection at block site
- Neuromuscular disease affecting evaluation.
- Chronic opioid use (\>30mg morphine equivalents/day)
- Cognitive impairment preventing pain reporting.
- Pregnancy
The study team makes the final eligibility decision.
Where it's taking place
- Barcelona, Barcelona, Spain
- Murcia, Murcia, Spain
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Barcelona, Barcelona, Spain; Murcia, Murcia, Spain. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.