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New treatment option for Breast Cancer
Official title Endoscopic Skin-Sparing vs. Conventional Mastectomy for Wound Complications in BC
ClinicalTrials.gov ID: NCT07548762
What this study is testing
- What it's testing
- This randomized, open-label study compares endoscopic skin-sparing mastectomy (E-SSM) with conventional mastectomy (CM) in female patients with unilateral invasive breast cancer (T1-4aN0-3M0). The primary objective is to evaluate differences in postoperative wound complications and patient satisfaction, with secondary outcomes including breast appearance and oncological safety.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 75, women only
You may be able to join if
- Female patients aged 18 to 75 years
- Pathologically confirmed invasive breast cancer
- Clinical stage cT1-4a N0-3 M0
- Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
- Unilateral breast cancer
You likely can't join if
- Tumor invasion of the skin
- Diffuse malignant microcalcifications
- Breast cancer during pregnancy or lactation
- History of another primary malignancy
- Severe cardiopulmonary, hepatic or renal dysfunction, or other significant systemic diseases
See the full eligibility criteria
- Female patients aged 18 to 75 years
- Pathologically confirmed invasive breast cancer
- Clinical stage cT1-4a N0-3 M0
- Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
- Unilateral breast cancer
- Left ventricular ejection fraction (LVEF) ≥ 50%
- Hematological and renal function with the following parameters: White blood cell count ≥ 3.0 × 10⁹/L; Neutrophil count ≥ 1.5 × 10⁹/L; Platelet count ≥ 100 × 10⁹/L; Hemoglobin ≥ 90 g/L; Serum creatinine ≤ 1.5 × upper...
- No planned breast reconstruction
- Tumor invasion of the skin
- Diffuse malignant microcalcifications
- Breast cancer during pregnancy or lactation
- History of another primary malignancy
- Severe cardiopulmonary, hepatic or renal dysfunction, or other significant systemic diseases
The study team makes the final eligibility decision.
Where it's taking place
- Guangzhou, Guangdong, China
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 75 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Guangzhou, Guangdong, China. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.