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Compares treatment options for Acne Vulgaris
Official title Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
ClinicalTrials.gov ID: NCT07544251
What this study is testing
What is Sarecycline?
Sarecycline is an investigational medicine, given as an once-daily pill taken by mouth, being studied as a potential treatment for acne vulgaris.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline. The bacteria in the gut and on the skin will be studied to see how each treatment may affect them and whether they change the profile of the bacteria that is present.
- Phase 4: studies an already-approved treatment
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 9 and older. Healthy volunteers may be eligible.
You may be able to join if
- 1) Diagnosis of acne vulgaris with:
- At least 10 inflammatory lesions (papules, pustules, and nodules) up to 100 noninflammatory lesions (open and closed comedones)
- No more than 2 nodules on the face
You likely can't join if
- Dermatological condition of face or facial hair that could interfere with clinical evaluations
- people who have used the following medications (topical refers only to the facial area) will not be eligible: 2a) Within 2 week prior to...
- Topical acne medications such as retinoids, antibiotics, hormonal modulators
- Topical benzoyl peroxide
- Topical anti-inflammatories and corticosteroids 2b) Within 4 weeks prior to randomization:
- Systemic antibiotics
See the full eligibility criteria
- 1) Diagnosis of acne vulgaris with:
- At least 10 inflammatory lesions (papules, pustules, and nodules) up to 100 noninflammatory lesions (open and closed comedones)
- No more than 2 nodules on the face
- Dermatological condition of face or facial hair that could interfere with clinical evaluations
- people who have used the following medications (topical refers only to the facial area) will not be eligible: 2a) Within 2 week prior to randomization:
- Topical acne medications such as retinoids, antibiotics, hormonal modulators
- Topical benzoyl peroxide
- Topical anti-inflammatories and corticosteroids 2b) Within 4 weeks prior to randomization:
- Systemic antibiotics
- Systemic acne treatments
- Oral probiotic supplement
- Systemic corticosteroids 2c) Within 12 weeks prior to randomization:
- Systemic retinoids 3) Individuals who have changed any of their hormonal based contraception or therapies within 3 months prior to joining the study. 4) Individuals who are pregnant or breastfeeding. 5) Individuals on...
The study team makes the final eligibility decision.
Where it's taking place
- Sacramento, California, United States
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 9 years and older. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Sacramento, California, United States. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.