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New treatment option for Azoospermia or Severe Oligozoospermia
Official title Fertility Restoration With Autografting of Cryopreserved Immature Testicular Tissue
ClinicalTrials.gov ID: NCT07542626
What this study is testing
- What it's testing
- This is a pilot clinical trial to evaluate the feasibility and outcome of autologous transplantation of immature testicular tissue cryopreserved during childhood as a method of fertility preservation for prepubertal boys in case of gonadotoxic therapies. Freezing of immature testicular tissue is performed since the early 2000s and a number of our patients have now reached reproductive age.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 40, men only
You may be able to join if
- all are required
- patients who have completed their gonadotoxic treatment
- patients who are in good health after care of the primary disease based on hemato-oncologist input
- patients with proven azoospermia in adulthood and child's wish requesting transplantation
- patients who cryopreserved and stored their immature testicular tissue (in conformity with regulatory requirements)
You likely can't join if
- patients for whom the cryostored tissue presents a non-negligible risk of cancer cells contamination
- patients presenting with a contraindication for general anethesia
See the full eligibility criteria
- all are required
- patients who have completed their gonadotoxic treatment
- patients who are in good health after care of the primary disease based on hemato-oncologist input
- patients with proven azoospermia in adulthood and child's wish requesting transplantation
- patients who cryopreserved and stored their immature testicular tissue (in conformity with regulatory requirements)
- in case of prior hematological malignant disease or metatstatic cancer, if the multidisciplinary assesment considers the risk of cancer cell contamination is negligible
- patients for whom the cryostored tissue presents a non-negligible risk of cancer cells contamination
- patients presenting with a contraindication for general anethesia
The study team makes the final eligibility decision.
Where it's taking place
- Brussels, Belgium
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 18 years to 40 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Brussels, Belgium. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.