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Compares treatment options for Postinduction Hypotension
Official title Continuous Versus Bolus Norepinephrine Administration to Treat Postinduction Hypotension
ClinicalTrials.gov ID: NCT07538388
What this study is testing
- What it's testing
- INDUCT-Multi is a multicenter randomized trial investigating whether continuous, compared to bolus, administration of norepinephrine during induction of general anesthesia reduces postinduction hypotension in high-risk non-cardiac surgery patients.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 45 and older
You may be able to join if
- We will include consenting patients ≥45 years scheduled for elective non-cardiac surgery under general anesthesia with planned continuous...
- Age ≥65 years
- ASA physical status III or IV
- Chronic arterial hypertension
- Diabetes mellitus requiring medication
You likely can't join if
- Pregnancy
- Cardiac arrhythmia
- History of intracranial hemorrhage or intracranial aneurysm
- Clinical indication for continuous norepinephrine infusion during induction of general anesthesia (e.g., severe aortic valve stenosis, coronary...
- Patients who are unable to understand, read, and provide informed consent in German
See the full eligibility criteria
- We will include consenting patients ≥45 years scheduled for elective non-cardiac surgery under general anesthesia with planned continuous intra-arterial blood pressure monitoring with a radial arterial catheter and with...
- Age ≥65 years
- ASA physical status III or IV
- Chronic arterial hypertension
- Diabetes mellitus requiring medication
- Intra-abdominal surgery
- Preoperative renal insufficiency (serum creatinine ≥1.2 mg/dL)
- Pregnancy
- Cardiac arrhythmia
- History of intracranial hemorrhage or intracranial aneurysm
- Clinical indication for continuous norepinephrine infusion during induction of general anesthesia (e.g., severe aortic valve stenosis, coronary artery disease, or heart failure)
- Patients who are unable to understand, read, and provide informed consent in German
The study team makes the final eligibility decision.
Where it's taking place
- Berlin, Germany
- Düsseldorf, Germany
- Hamburg, Germany
- München, Germany
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 45 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Berlin, Germany; Düsseldorf, Germany; Hamburg, Germany; München, Germany. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.