New treatment option for Lichen Planopilaris
Official title A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
ClinicalTrials.gov ID: NCT07532603
What this study is testing
What is Oral Brepocitinib?
Oral Brepocitinib is an investigational medicine, given as a pill taken by mouth, being studied as a potential treatment for lichen planopilaris.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with lichen planopilaris
- Phase 3: a large, late-stage study
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Age ≥ 18 years
- Scalp biopsy consistent with LPP
- Active and symptomatic LPP at screening and baseline-
- Weight \> 40 kg to \< 130 kg with BMI ≤ 45 kg/m2
You likely can't join if
- History of: Lymphoproliferative disorder; Active malignancy; History of cancer within 5 years prior to baseline (exceptions for basal cell carcinoma...
- High risk of thrombosis or cardiovascular disease
- High risk of herpes zoster
- Active or recent infection
The study team makes the final eligibility decision.
Where it's taking place
- Birmingham, Alabama, United States
- Phoenix, Arizona, United States
- Scottsdale, Arizona, United States
- Irvine, California, United States
- Oakland, California, United States
- Sacramento, California, United States
- San Francisco, California, United States
- Denver, Colorado, United States
- Farmington, Connecticut, United States
- New Haven, Connecticut, United States
- Miami, Florida, United States
- Chicago, Illinois, United States
- Skokie, Illinois, United States
- Clarksville, Indiana, United States
- Indianapolis, Indiana, United States
- Leawood, Kansas, United States
- Louisville, Kentucky, United States
- Boston, Massachusetts, United States
- Burlington, Massachusetts, United States
- Ann Arbor, Michigan, United States
+ 37 more site(s).
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Birmingham, Alabama, United States; Phoenix, Arizona, United States; Scottsdale, Arizona, United States; Irvine, California, United States; Oakland, California, United States; Sacramento, California, United States and 51 more location(s). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.