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New treatment option for Phenylketonuria
Official title Effect of Different Meal Types Given Before Exercise on Plasma Amino Acid Levels and Metabolic Control Parameters in Classical Phenylketonuria Patients Undergoing Aerobic and Resistance Exercises
ClinicalTrials.gov ID: NCT07526909
What this study is testing
- What it's testing
- This study will be the first in the literature to evaluate the relationship between aerobic and resistance exercises, plasma amino acid levels, metabolic control of patients, and the metabolic response to exercise with different types of meals in patients with Phenylketonuria (PKU). In patients with phenylketonuria, the aim is to determine which pre-exercise dietary recommendations are more physiologically appropriate and ideal for achieving good metabolic control.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Be over 18 years old,
- Having a classic FKU diagnosis,
- Not being actively engaged in sports,
- Not having any other existing diseases,
- Not having an active infection,
You likely can't join if
- Presence of a chronic disease accompanying FKU disease (endocrine, etc.)
- The individual with FKU has mental retardation or is deemed unfit for work based on psychomotor assessment,
- Recent weight loss, history of hospitalisation, a past infection, or a diagnosed illness
- Use of drugs or alcohol that alter protein and energy metabolism (e.g., corticosteroids, etc.)
- Pregnancy status
- Smoking habits The considerations to be taken into account when planning the day/date of the test are as follows.
See the full eligibility criteria
- Be over 18 years old,
- Having a classic FKU diagnosis,
- Not being actively engaged in sports,
- Not having any other existing diseases,
- Not having an active infection,
- Have a BMI in the range of 20-28 kg/m2 within the last 3 months,
- Agreeing to consume test meals and provide blood samples for parameters that will evaluate plasma amino acid levels as part of the research
- Being willing to participate in this study
- Presence of a chronic disease accompanying FKU disease (endocrine, etc.)
- The individual with FKU has mental retardation or is deemed unfit for work based on psychomotor assessment,
- Recent weight loss, history of hospitalisation, a past infection, or a diagnosed illness
- Use of drugs or alcohol that alter protein and energy metabolism (e.g., corticosteroids, etc.)
- Pregnancy status
- Smoking habits The considerations to be taken into account when planning the day/date of the test are as follows.
- Having engaged in heavy exercise or sports within 24 hours before the application of test diets,
- Being in the menstrual period for female patients.
The study team makes the final eligibility decision.
Where it's taking place
- Ankara, Ankara, Turkey (Türkiye)
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ankara, Ankara, Turkey (Türkiye). Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.