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New treatment option for Cerebral Palsy
Official title Antenatal Magnesium Sulphate in High-Risk Preterm Patients
ClinicalTrials.gov ID: NCT07524972
What this study is testing
What is Magnesium sulfate?
Magnesium sulfate is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for cerebral palsy.
Also referred to as MgSO₄.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The goal of this clinical trial is to evaluate whether antenatal magnesium sulphate reduces the risk of cerebral palsy in infants born to women at high risk of preterm birth. It will also assess the safety of magnesium sulfate for both the mother and the neonate.
- Phase 3: a large, late-stage study
- You might receive a placebo (an inactive treatment) instead of the study drug, decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 45, women only
You may be able to join if
- Pregnant women at high risk of preterm birth between 32 and 35 weeks of gestation
- Birth is planned or expected within 24 hours
- Singleton pregnancy
- No contraindication to antenatal magnesium sulphate
- Able to provide informed consent
You likely can't join if
- Higher-order multiple pregnancy
- Received antenatal magnesium sulphate during the current pregnancy for hypertension or preeclampsia
- Magnesium sulphate is required for treatment of preeclampsia
- Second stage of labor
- Respiratory rate less than 16 breaths per minute
- Absent patellar reflexes
See the full eligibility criteria
- Pregnant women at high risk of preterm birth between 32 and 35 weeks of gestation
- Birth is planned or expected within 24 hours
- Singleton pregnancy
- No contraindication to antenatal magnesium sulphate
- Able to provide informed consent
- Higher-order multiple pregnancy
- Received antenatal magnesium sulphate during the current pregnancy for hypertension or preeclampsia
- Magnesium sulphate is required for treatment of preeclampsia
- Second stage of labor
- Respiratory rate less than 16 breaths per minute
- Absent patellar reflexes
- Urine output less than 100 mL in the previous 4 hours
- Renal failure
- Hypocalcemia
- Myasthenia gravis
- Magnesium sulphate infusion had to be stopped because of adverse effects
The study team makes the final eligibility decision.
Where it's taking place
- Ismailia, Ismailia Governorate, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling female, 18 years to 45 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Ismailia, Ismailia Governorate, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.