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Compares treatment options for Theophylline
Official title Theophylline, Versus Sumatriptan and Gabapentin in The Treatment of Post-Dural Puncture Headache
ClinicalTrials.gov ID: NCT07515456
What this study is testing
What is Theophylline?
Theophylline is an investigational medicine, given as an infusion into a vein, being studied as a potential treatment for theophylline.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- The aim of this study is to compare the safety and efficacy of theophylline, sumatriptan, and gabapentin in the treatment of post-dural puncture headache.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 21 to 50
You may be able to join if
- Age from 21 to 50 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status ≤ II.
- Patient's selection for this study will be based on clinical diagnosis suggesting post-dural puncture headache (PDPH) based on the International...
- Patients with numeric rating scale (NRS) of ≥ 5.
You likely can't join if
- Pregnant women.
- History of; chronic headache, cluster headache, migraine, convulsions, cerebrovascular accident, and previous neurological diseases.
- Signs of meningismus.
- Dysrhythmia.
- Hypertension.
- Ischemic heart disease.
See the full eligibility criteria
- Age from 21 to 50 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status ≤ II.
- Patient's selection for this study will be based on clinical diagnosis suggesting post-dural puncture headache (PDPH) based on the International Headache Society criteria.
- Patients with numeric rating scale (NRS) of ≥ 5.
- Pregnant women.
- History of; chronic headache, cluster headache, migraine, convulsions, cerebrovascular accident, and previous neurological diseases.
- Signs of meningismus.
- Dysrhythmia.
- Hypertension.
- Ischemic heart disease.
- Hyperthyroidism.
- Peripheral vascular disease (ischemic colitis).
- Liver or renal impairment.
- Use of selective serotonin reuptake inhibitors.
- Use of ergotamine derivatives in the past 24 hours.
- Use of monoamine oxidase inhibitors in the last 2 weeks.
- Use of any kind of opiates.
- Allergy to the study medications and any contraindication of oral intake.
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, El-Gharbia, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 21 years to 50 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, El-Gharbia, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.