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New treatment option for Skin Cancer
Official title Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
ClinicalTrials.gov ID: NCT07510061
What this study is testing
- What it's testing
- The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans. Excess morbidity and mortality during heat waves provides strong evidence for fatal outcomes.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 to 65. Healthy volunteers may be eligible.
You may be able to join if
- Study Population Healthy adult volunteers residing in Denmark (Northern Europe) or Greece (Southern Europe).
- Age 18-65 years (or your protocol-specific age range)
- Healthy as determined by medical history screening questionnaire
- Able to provide written informed consent
- Able to complete heat exposure and light exercise protocol
You likely can't join if
- History of cardiovascular, metabolic, neurological, or dermatological disease
- History of heat-related illness (e.g., heat stroke)
- Use of medications affecting thermoregulation or cardiovascular function
- Smoking or substance abuse
- Pregnancy or breastfeeding
- Abnormal ECG or uncontrolled hypertension
See the full eligibility criteria
- Study Population Healthy adult volunteers residing in Denmark (Northern Europe) or Greece (Southern Europe).
- Age 18-65 years (or your protocol-specific age range)
- Healthy as determined by medical history screening questionnaire
- Able to provide written informed consent
- Able to complete heat exposure and light exercise protocol
- No heat acclimatization or extensive sun exposure in the previous 4 weeks
- Fitzpatrick skin type I-IV (if applicable for UV testing)
- Willing to undergo blood sampling, urine collection, and skin biopsy
- History of cardiovascular, metabolic, neurological, or dermatological disease
- History of heat-related illness (e.g., heat stroke)
- Use of medications affecting thermoregulation or cardiovascular function
- Smoking or substance abuse
- Pregnancy or breastfeeding
- Abnormal ECG or uncontrolled hypertension
- Recent severe sunburn or UV treatment
- Contraindications to skin biopsy
- Inability to tolerate heat exposure during screening
The study team makes the final eligibility decision.
Where it's taking place
- Copenhagen, Denmark
- Trikala, Thessaly, Greece
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years to 65 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Copenhagen, Denmark; Trikala, Thessaly, Greece. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.