BridgeMD
Compares treatment options for Alveolar Bone Loss
Official title Evaluation of Stem Cell Exosomes Versus Platelet-Rich Fibrin in Tooth Extraction Socket Healing
ClinicalTrials.gov ID: NCT07508033
What this study is testing
What is MSC-Derived Exosomes?
MSC-Derived Exosomes is an investigational medicine, being studied as a potential treatment for alveolar bone loss.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- This study evaluates two different treatments used to help the jawbone heal after a tooth is removed. When a tooth is extracted, the surrounding bone often shrinks, which can make it difficult to place dental implants later.
- Phase 2: a mid-size study of how well it works
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 20 to 45. Healthy volunteers may be eligible.
You may be able to join if
- Patients aged between 20 and 45 years.
- Patients requiring a single tooth extraction of a non-infected tooth in the aesthetic zone (incisors, canines) or premolar area.
- Presence of adjacent teeth to the extraction site.
- Adequate oral hygiene (Plaque Index \< 20%).
- Patients willing and able to comply with the follow-up schedule and 3-month CBCT scan.
You likely can't join if
- Patients with systemic diseases that contraindicate oral surgery or interfere with bone healing (e.g., uncontrolled diabetes, osteoporosis...
- History of head and neck radiation therapy or bisphosphonate medication use.
- Active infection or acute abscess at the extraction site.
- Heavy smokers (more than 10 cigarettes per day).
- Pregnant or lactating women.
- Patients with poor oral hygiene or active periodontal disease in the rest of the mouth.
See the full eligibility criteria
- Patients aged between 20 and 45 years.
- Patients requiring a single tooth extraction of a non-infected tooth in the aesthetic zone (incisors, canines) or premolar area.
- Presence of adjacent teeth to the extraction site.
- Adequate oral hygiene (Plaque Index \< 20%).
- Patients willing and able to comply with the follow-up schedule and 3-month CBCT scan.
- Signed informed consent provided by the participant.
- Patients with systemic diseases that contraindicate oral surgery or interfere with bone healing (e.g., uncontrolled diabetes, osteoporosis, hyperparathyroidism).
- History of head and neck radiation therapy or bisphosphonate medication use.
- Active infection or acute abscess at the extraction site.
- Heavy smokers (more than 10 cigarettes per day).
- Pregnant or lactating women.
- Patients with poor oral hygiene or active periodontal disease in the rest of the mouth.
- Use of any medications known to affect bone metabolism (e.g., long-term corticosteroids).
The study team makes the final eligibility decision.
Where it's taking place
- Tanta, Gharbia Governorate, Egypt
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 20 years to 45 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Tanta, Gharbia Governorate, Egypt. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.