Recruiting NA Respiratory Failure With Hypoxia

New treatment option for Respiratory Failure With Hypoxia

Official title Physiological Study of High PEEP in Noninvasive Ventilation

ClinicalTrials.gov ID: NCT07503509

What this study is testing

What it's testing
To investigate the physiological effects of high positive end-expiratory pressure (PEEP) during noninvasive ventilation in patients with hypoxemic respiratory failure, and to elucidate the mechanisms underlying high PEEP-induced improvement in oxygenation.

A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.

Who can take part

Ages 18 to 100

You may be able to join if

  • Age ≥ 18 years
  • PaCO₂ ≤ 50 mmHg
  • PaO₂/FiO₂ ≤ 300 mmHg
  • Use of a noninvasive ventilator with esophageal pressure monitoring capability (e.g., Mindray SV70) -

You likely can't join if

  • Respiratory failure caused by heart failure, asthma, or acute exacerbation of chronic obstructive pulmonary disease (COPD) (COPD as a comorbidity may...
  • Pneumothorax
  • Patients who refuse to participate in this trial -

The study team makes the final eligibility decision.

Where it's taking place

  • Chongqing, Chongqing Municipality, China

Questions & answers

Do participants get paid in this trial?

This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.

Is it free to join, and do I need insurance?

Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.

How long does this study last?

The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.

Who can join this trial?

This study is enrolling all sexes, 18 years to 100 years. The study team makes the final eligibility decision.

Where is this trial taking place?

Study sites include Chongqing, Chongqing Municipality, China. Enter your location above to see the nearest site and check your eligibility.

Explore other conditions

BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.