BridgeMD
New treatment option for Aging
Official title Project SIRT6 Activator
ClinicalTrials.gov ID: NCT07500649
What this study is testing
- What it's testing
- The global ageing population is increasingly affected by age-related diseases, which are challenging healthcare systems. Current treatments often extend lifespan without improving healthspan.
- You might receive a placebo (an inactive treatment) instead of the study drug.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 50 to 80, men only. Healthy volunteers may be eligible.
You may be able to join if
- 50-80 years males;
- Resident of Singapore (citizenship or permanent residency is not required);
- Prefrail according to Fried frailty phenotype score;
- English-literate who can understand, read and write in English;
- Individuals without severe cognitive impairment, as determined by PI judgment;
You likely can't join if
- Pre-existing or history of major cardiovascular disease (e.g., coronary artery disease, heart failure, stroke, peripheral vascular disease);
- Current cancer or non-stable chronic obstructive pulmonary disease (COPD);
- Use of anticoagulant medication;
- Consuming seaweed more than 3 times a week;
- Having hairiness, moles, tattoos, scars, irritated skin, etc. on the face which could influence the investigation;
- Having used within the 3 past weeks for more than 3 consecutive days any systemic or topical drugs related to antibiotics or having planned to use...
See the full eligibility criteria
- 50-80 years males;
- Resident of Singapore (citizenship or permanent residency is not required);
- Prefrail according to Fried frailty phenotype score;
- English-literate who can understand, read and write in English;
- Individuals without severe cognitive impairment, as determined by PI judgment;
- Apparently healthy and non-smokers having not more than 2 of the following conditions. If the conditions are present they have to be stable:
- Hypertension,
- Hyperlipidemia,
- Hyperglycemia,
- Osteopenia/osteoporosis,
- Osteoarthritis,
- COPD,
- Type 2 diabetes. people who agree to shave one day before each visit if he has dense facial hairs on their cheeks that could interfere with skin microbiome sampling.
- Pre-existing or history of major cardiovascular disease (e.g., coronary artery disease, heart failure, stroke, peripheral vascular disease);
- Current cancer or non-stable chronic obstructive pulmonary disease (COPD);
- Use of anticoagulant medication;
- Consuming seaweed more than 3 times a week;
- Having hairiness, moles, tattoos, scars, irritated skin, etc. on the face which could influence the investigation;
- Having used within the 3 past weeks for more than 3 consecutive days any systemic or topical drugs related to antibiotics or having planned to use these treatments during the study;
- Having a positive serology for HIV, HEPATITIS B, HEPATITIS C\ \ people will undergo a serology test, which will be conducted at baseline and at the end of the intervention visit. Only for people who accepted to undergo...
- Subject with any contra-indication for skin microbiopsies:
- hypersensitivity or any serious reaction to local anesthesia; (lidocaine/prilocaine), local antibiotics, and antiseptics,
- with inherited or acquired hemostasis disorders,
- having had any treatment which may affect the blood coagulation and hemostasis (anti-coagulant medications…),
- having a history of wound healing defects (hypertrophic scars, keloids…).
The study team makes the final eligibility decision.
Where it's taking place
- Singapore, Singapore, Singapore
- Singapore, Singapore
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling male, 50 years to 80 years. Healthy volunteers may be eligible. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Singapore, Singapore, Singapore; Singapore, Singapore. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.