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New treatment option for Sarcoidosis
Official title Corticosteroid Tapering in Sarcoidosis
ClinicalTrials.gov ID: NCT07498842
What this study is testing
What is Standard prednisolone taper?
Standard prednisolone taper is an investigational medicine, being studied as a potential treatment for sarcoidosis.
Plain-language explanation of the investigational treatment - it is being studied and is not an approved or proven therapy. The study team can confirm the details.
- What it's testing
- Sarcoidosis is an inflammatory condition affecting many different parts of the body but most commonly the lungs. It is not known what causes sarcoidosis.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 18 and older
You may be able to join if
- Confirmed sarcoidosis by: (a) Histological diagnosis and/or (b) Multidisciplinary Team (MDT) diagnosis
- Prednisolone 5-10mg/day for \> 6 months
- Clinically stable disease for \> 6 months (no flares or dose escalation)
- On or off second-line agent
- \> 18 years old
You likely can't join if
- Cardiac or neurosarcoidosis
- Advanced pulmonary sarcoidosis defined as either: (a) composite physiological index (CPI) \> 40 (b) pulmonary hypertension
- Active sarcoidosis flare or dose escalation in the past 6 months
- Known adrenal insufficiency
- Pregnancy or breastfeeding
- Previous or current infliximab use
See the full eligibility criteria
- Confirmed sarcoidosis by: (a) Histological diagnosis and/or (b) Multidisciplinary Team (MDT) diagnosis
- Prednisolone 5-10mg/day for \> 6 months
- Clinically stable disease for \> 6 months (no flares or dose escalation)
- On or off second-line agent
- \> 18 years old
- Written informed consent provided
- Cardiac or neurosarcoidosis
- Advanced pulmonary sarcoidosis defined as either: (a) composite physiological index (CPI) \> 40 (b) pulmonary hypertension
- Active sarcoidosis flare or dose escalation in the past 6 months
- Known adrenal insufficiency
- Pregnancy or breastfeeding
- Previous or current infliximab use
The study team makes the final eligibility decision.
Where it's taking place
- London, United Kingdom
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 18 years and older. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include London, United Kingdom. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.