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New treatment option for Frailty at Older Adults
Official title A Novel Multi-Modal Approach to Promote Functional Outcomes in Cognitively Frail Older Adults
ClinicalTrials.gov ID: NCT07497334
What this study is testing
- What it's testing
- The goal of this clinical trial is to explore the effects of intermittent theta burst stimulation (iTBS) primed with theta burst stimulation (cTBS), on top of aerobic exercise, on cognitive function, mobility, and brain activity in older adults with cognitive frailty. Understanding these effects will help us develop intervention models that benefit cognitively frail older adults.
- Which group you join is decided by chance.
A plain-language read of the study's public ClinicalTrials.gov listing. The study team confirms the details.
Who can take part
Ages 60 to 90
You may be able to join if
- be between 60 and 90 years old;
- scored \< 9/12 on the SPPB;
- scored \>18/30 on the MoCA;
- scored \>9/42 on the PFFS;
- lived in the community;
You likely can't join if
- have magnetic resonance imaging (MRI) contraindications;
- have aerobic exercise contraindications;
- have transcranial magnetic stimulation contraindications;
- be diagnosed with neurodegenerative conditions (i.e., dementia, Parkinson's, Alzheimer's disease, Amyotrophic lateral sclerosis, and stroke);
- live in a nursing home or other care facilities/institutions;
- bed taking fixed dose of medication or had been taking medications known to potentially affect cognitive and physical function (e.g., psychotropic...
See the full eligibility criteria
- be between 60 and 90 years old;
- scored \< 9/12 on the SPPB;
- scored \>18/30 on the MoCA;
- scored \>9/42 on the PFFS;
- lived in the community;
- be able to ambulate up to four meters with or without assistive devices;
- be able to provide written informed consent on their own behalf;
- can understand verbal and written Cantonese and/or English.
- have magnetic resonance imaging (MRI) contraindications;
- have aerobic exercise contraindications;
- have transcranial magnetic stimulation contraindications;
- be diagnosed with neurodegenerative conditions (i.e., dementia, Parkinson's, Alzheimer's disease, Amyotrophic lateral sclerosis, and stroke);
- live in a nursing home or other care facilities/institutions;
- bed taking fixed dose of medication or had been taking medications known to potentially affect cognitive and physical function (e.g., psychotropic medications), as identified through a review of their medication lists...
- have a history indicative of carotid sinus sensitivity (i.e., falls due to loss of consciousness);
- cancer and undergo radiation therapy.
The study team makes the final eligibility decision.
Where it's taking place
- Hong Kong, Hong Kong
Questions & answers
Do participants get paid in this trial?
This listing doesn't specify compensation. Many trials still reimburse travel or offer a stipend, so it's worth asking the study team when you connect.
Is it free to join, and do I need insurance?
Searching and applying through BridgeMD is free. In clinical trials the study-related treatment and visits are generally provided at no cost to you. You usually don't need insurance to take part - confirm specifics with the study team.
How long does this study last?
The listing doesn't state an exact length. The study team walks you through the schedule and number of visits before you decide to enroll.
Who can join this trial?
This study is enrolling all sexes, 60 years to 90 years. The study team makes the final eligibility decision.
Where is this trial taking place?
Study sites include Hong Kong, Hong Kong. Enter your location above to see the nearest site and check your eligibility.
Explore other conditions
BridgeMD is an information and trial-matching tool - not medical advice, and not the study sponsor. Details come from ClinicalTrials.gov; the study team decides eligibility.